ArticleProceedings. Biological sciences2019
Imperfect vaccine and hysteresis.
Article in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Social imitation dynamics of vaccination driven by vaccine effectiveness and beliefs.PLoS computational biology · 2025Article
- Revealing the complex dynamics of monkeypox epidemics in heterogeneous networks by the evolutionary game theory.Scientific reports · 2025Article
- Collective cooperative intelligence.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Adaptive human behavior and delays in information availability autonomously modulate epidemic waves.PNAS nexus · 2025Article
- Behavior changes influence mpox transmission in the United States, 2022-2023: Insights from homogeneous and heterogeneous models.PNAS nexus · 2025Article
- Balancing fairness and efficiency in dynamic vaccine allocation during major infectious disease outbreaks.Scientific reports · 2025Article
- Modeling and analysis of infectious diseases based on behavioral game theory on two-layered networks under media coverage.PloS one · 2025Article
- Social dilemma of nonpharmaceutical interventions: Determinants of dynamic compliance and behavioral shifts.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Adaptive human behaviour modulates the impact of immune life history and vaccination on long-term epidemic dynamics.Proceedings. Biological sciences · 2024Article
- Predicting Covid-19 pandemic waves with biologically and behaviorally informed universal differential equations.Heliyon · 2024Article
- Evolution of conditional cooperation in collective-risk social dilemma with repeated group interactions.Proceedings. Biological sciences · 2023Article
- Population heterogeneity in vaccine coverage impacts epidemic thresholds and bifurcation dynamics.Heliyon · 2023Article
- Nonlinear eco-evolutionary games with global environmental fluctuations and local environmental feedbacks.PLoS computational biology · 2023Article
- A cyclic behavioral modeling aspect to understand the effects of vaccination and treatment on epidemic transmission dynamics.Scientific reports · 2023Article
- Article
- The impact of the self-recognition ability and physical quality on coupled negative information-behavior-epidemic dynamics in multiplex networks.Chaos, solitons, and fractals · 2023Article
- Proposing a New Conceptual Syndemic Framework for COVID-19 Vaccine Hesitancy: A Narrative Review.International journal of environmental research and public health · 2023Review
- Overcoming vaccine hesitancy by multiplex social network targeting: an analysis of targeting algorithms and implications.Applied network science · 2023Article
- Social dilemmas of sociality due to beneficial and costly contagion.PLoS computational biology · 2022Article
- Emergence of protective behaviour under different risk perceptions to disease spreading.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Addressing vaccine compliance problems is of particular relevance and significance to public health. Despite resurgence of vaccine-preventable diseases and public awareness of vaccine importance, why is it so challenging to boost population vaccination coverage to desired levels especially in the wake of declining vaccine uptake? To understand this puzzling phenomenon, here we study how social imitation dynamics of vaccination can be impacted by the presence of imperfect vaccine, which only confers partial protection against the disease. Besides weighing the perceived cost of vaccination with the risk of infection, the effectiveness of vaccination is also an important factor driving vaccination decisions. We discover that there can exist multiple stable vaccination equilibria if vaccine efficacy is below a certain threshold. Furthermore, our bifurcation analysis reveals the occurrence of hysteresis loops of vaccination rate with respect to changes in the perceived vaccination cost as well as in the vaccination effectiveness. Moreover, we find that hysteresis is more likely to arise in spatial populations than in well-mixed populations, even for parameter choices that do not allow for bifurcation in the latter. Our work shows that hysteresis can appear as an unprecedented roadblock for the recovery of vaccination uptake, thereby helping explain the persistence of vaccine compliance problem.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.