ArticleInternational journal of cancer2020
Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics.
Open access · bronzeAbstract read
In one paragraph
Article in International journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 21% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Fully exploiting SNP arrays: a systematic review on the tools to extract underlying genomic structure.Briefings in bioinformatics · 2022Pooled it
- Major Ethnic Populations Are Significantly Differentiated at the Glioblastoma Multiforme Candidate Loci.International journal of molecular sciences · 2026Article
- The safety and efficacy of bispecific T-cell engagers (TCEs) in patients with glioma.Clinical and experimental medicine · 2026Review
- Gaps in Diagnosis, Treatment, and Outcomes Among Patients with Brain Tumors in the United States: A State-of-the-Art Review.Cancers · 2025Review
- Race and "omic" data in glioma: A systematic review of contemporary research to explore the digital divide.Neuro-oncology practice · 2025Article
- Understanding Neovascularization in Glioblastoma: Insights from the Current Literature.International journal of molecular sciences · 2025Review
- Optimization of computational ancestry inference for use in cancer cell lines.Biology methods & protocols · 2025Article
- High costs, low quality of life, reduced survival, and room for improving treatment: an analysis of burden and unmet needs in glioma.Frontiers in oncology · 2024Review
- WDR82-Mediated H3K4me3 Is Associated with Tumor Proliferation and Therapeutic Efficacy in Pediatric High-Grade Gliomas.Cancers · 2023Article
- The joint impacts of sex and race/ethnicity on incidence of grade 1 versus grades 2-3 meningioma across the lifespan.Neuro-oncology advances · 2023Article
- Influence of county-level geographic/ancestral origin on glioma incidence and outcomes in US Hispanics.Neuro-oncology · 2023Article
- Localized variation in ancestral admixture identifies pilocytic astrocytoma risk loci among Latino children.PLoS genetics · 2022Article
- Racial/ethnic and sex differences in young adult malignant brain tumor incidence by histologic type.Cancer epidemiology · 2022Article
- Haplotypes of single cancer driver genes and their local ancestry in a highly admixed long-lived population of Northeast Brazil.Genetics and molecular biology · 2022Article
- Epidemiology of Brain and Other CNS Tumors.Current neurology and neuroscience reports · 2021Review
- The histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3).Neuro-oncology · 2021Article
- Recent incidence trend of elderly patients with glioblastoma in the United States, 2000-2017.BMC cancer · 2021Article
- European genetic ancestry associated with risk of childhood ependymoma.Neuro-oncology · 2020Article
- Risk factors for childhood and adult primary brain tumors.Neuro-oncology · 2019Review
- GATAD1 gene amplification promotes glioma malignancy by directly regulating CCND1 transcription.Cancer medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 20 institutions in 5 countries.
Quinn T OstromDepartment of Medicine, Section of Epidemiology and Population Sciences, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX.
Kathleen M EganDivision of Population Sciences, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
L Burt NaborsNeuro-Oncology Program, University of Alabama at Birmingham, Birmingham, AL.
Travis GerkeDivision of Population Sciences, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Reid C ThompsonDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN.
Jeffrey J OlsonDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA.
Renato LaRoccaDepartment of Hematology-Oncology, Norton Cancer Institute, Louisville, KY.
Sajeel ChowdharyNeuro-Oncology Program, Lynn Cancer Institute, Boca Raton, FL.
Jeanette E Eckel-PassowDivision of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, MN.
Georgina ArmstrongDepartment of Medicine, Section of Epidemiology and Population Sciences, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX.
John K WienckeDepartment of Neurological Surgery, School of Medicine, University of California, San Francisco, San Francisco, CA.
Jonine L BernsteinDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, NY, New York.
Elizabeth B ClausSchool of Public Health, Yale University, New Haven, CT.
Dora Il'yasovaDepartment of Epidemiology and Biostatistics, School of Public Health, Georgia State University, Atlanta, GA.
Christoffer JohansenOncology Clinic, Finsen Center, Rigshospitalet and Survivorship Research Unit, The Danish Cancer Society Research Center, Copenhagen, Denmark.
Daniel H LachanceDepartment of Neurology, Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN.
Rose K LaiDepartment of Neurology and Preventive Medicine, Keck School of Medicine, University of Southern California, CA, Los Angeles.
Ryan T MerrellDepartment of Neurology, NorthShore University HealthSystem, Evanston, IL.
Sara H OlsonDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, NY, New York.
Siegal SadetzkiCancer and Radiation Epidemiology Unit, Gertner Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA.
Sanjay SheteDepartment of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX.
Richard S HoulstonDivision of Genetics and Epidemiology, The Institute of Cancer Research in Sutton, Surrey, United Kingdom.
Robert B JenkinsDepartment of Laboratory Medicine and Pathology, Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN.
Margaret R WrenschDepartment of Neurological Surgery, School of Medicine, University of California, San Francisco, San Francisco, CA.
Beatrice MelinDepartment of Radiation Sciences, Umeå University, Umeå, Sweden.
Christopher I AmosInstitute for Clinical and Translational Research, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX.
Jason T HuseDepartment of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX.
Jill S Barnholtz-SloanCase Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH.
Melissa L BondyDepartment of Medicine, Section of Epidemiology and Population Sciences, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX.
Baylor College of Medicine · USMemorial Sloan Kettering Cancer Center · USMoffitt Cancer Center · USThe University of Texas MD Anderson Cancer Center · USBrigham and Women's Hospital · USCase Western Reserve University · USDuke University · USEmory University · USHouston Institute for Clinical Research · USInstitute of Cancer Research · GBLynn University · USMayo Clinic · USMayo Clinic in Arizona · USMayo Clinic in Florida · USNeurological Surgery · USNorthShore University HealthSystem · USNorton Healthcare · USRigshospitalet · DKSheba Medical Center · ILUmeå University · SE
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MTumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8MTRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5MTumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9MTissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang · 2002 to 2026
$57.4MTropism Enhanced Oncolytic Adenovirus for the Treatment of Brain TumorsP50CA127001 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Juan Fueyo · 2008 to 2026
$41.2MGENETIC EPIDEMIOLOGY OF MALIGNANT GLIOMAR01CA052689 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WIENCKE, JOHN K., WRENSCH, MARGARET R. · 1991 to 2015
$20.5MInternational Case Control Study of Malignant GliomaR01CA139020 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BONDY, MELISSA L. · 2010 to 2015
$16.0MGenetic Epidemiology of Glioma International ConsortiumR01CA119215 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BONDY, MELISSA L. · 2006 to 2010
$11.9MSoutheast Region Case-Control Study of Adult GliomaR01CA116174 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI EGAN, KATHLEEN M. · 2007 to 2011
$4.9MHelping Neuro-oncologists Navigate Expanded AccessR01CA217105 · NCI · STANFORD UNIVERSITY · PI BAINBRIDGE, MATTHEW NEIL, BONDY, MELISSA L. · 2018 to 2024
$4.7MImmune epigenetic biomarkers of survival in glioma epidemiologyR01CA207360 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WIENCKE, JOHN K. · 2017 to 2021
$3.8MNCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016672NCI NIH HHS P30 CA076292NCI NIH HHS P30 CA125123NCI NIH HHS P50 CA097257NCI NIH HHS P50 CA127001NCI NIH HHS R01 CA052689NCI NIH HHS R01 CA116174NCI NIH HHS R01 CA119215NCI NIH HHS R01 CA139020NCI NIH HHS R01 CA207360NCI NIH HHS R01 CA207972NCI NIH HHS R01CA207972NCI NIH HHS R01 CA217105
Abstract
Glioma incidence is highest in non-Hispanic Whites, and to date, glioma genome-wide association studies (GWAS) to date have only included European ancestry (EA) populations. African Americans and Hispanics in the US have varying proportions of EA, African (AA) and Native American ancestries (NAA). It is unknown if identified GWAS loci or increased EA is associated with increased glioma risk. We assessed whether EA was associated with glioma in African Americans and Hispanics. Data were obtained for 832 cases and 675 controls from the Glioma International Case-Control Study and GliomaSE Case-Control Study previously estimated to have <80% EA, or self-identify as non-White. We estimated global and local ancestry using fastStructure and RFMix, respectively, using 1,000 genomes project reference populations. Within groups with ≥40% AA (AFR
Indexed as
Black or African AmericanCase-Control StudiesFemaleGenetic Association StudiesGenetic LociGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeGliomaHispanic or LatinoHumansMaleMiddle AgedPolymorphism, Single NucleotideRiskWhite Peoplegenetic ancestrygenetic epidemiologygenome-wide association studyglioma
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.