ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019
Working memory in posterior cortical atrophy.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy.Scientific reports · 2021Trial
- Posterior cortical atrophy: reorganization of the dorsal attention network and its implications on volume loss and clinical performance.Journal of neurology · 2025Article
- Social cognition and behavioral changes in patients with posterior cortical atrophy.Journal of neurology · 2024Article
- Primary and Secondary Progressive Aphasia in Posterior Cortical Atrophy.Life (Basel, Switzerland) · 2022Article
- What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy.Frontiers in human neuroscience · 2021Article
- Benson's Disease or Posterior Cortical Atrophy, Revisited.Journal of Alzheimer's disease : JAD · 2021Review
- Impairments of auditory scene analysis in posterior cortical atrophy.Brain : a journal of neurology · 2020Article
- The impact of white matter hyperintensities on speech perception.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Establishing two principal dimensions of cognitive variation in logopenic progressive aphasia.Brain communications · 2020Article
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Authors and funding
4 authors.
Funding
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Abstract
We used an ad hoc created neuropsychological battery to evaluate in details both verbal and visuospatial working memory (WM) in patients with posterior cortical atrophy (PCA, n = 5). PCA is a rare, early-onset neurodegenerative dementia, often due to Alzheimer's disease (AD) pathology. Clinically, PCA patients present with visual, visuospatial, and visuomotor deficits, and no memory complaints. PCA patients' patterns of performance were compared with those of 11 typical, amnestic AD patients matched for disease severity, as well as with 17 age-matched healthy controls. Both groups of patients had impaired WM performance compared to controls. However, PCA patients were more impaired than typical AD patients for both verbal and visuospatial WM. Moreover, PCA patients showed a more consistent impairment of visuospatial WM, as compared with verbal WM. Systematic WM evaluation should be part of the standard assessment in PCA. WM deficits affect patients' quality of life and can be detrimental to rehabilitation programs.
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