Evidence map›Paper›PMID 30963272›Full record

ArticleEuropean radiology2019

Magnetic resonance imaging radiomics in categorizing ovarian masses and predicting clinical outcome: a preliminary study.

He Zhang, Yunfei Mao, Xiaojun Chen, Guoqing Wu, Xuefen Liu, Peng Zhang, Yu Bai, Pengcong Lu, Weigen Yao, Yuanyuan Wang and 2 more

Abstract readEvaluation Study
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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  12. CT-based radiomics model to predict platinum sensitivity in epithelial ovarian carcinoma: a multicentre study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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  14. Multimodal ultrasound-based radiomics and deep learning for differential diagnosis of O-RADS 4-5 adnexal masses.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
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  16. Radiomics analysis of ultrasound images to discriminate between benign and malignant adnexal masses with solid morphology on ultrasound.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

He ZhangDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.
Yunfei MaoDepartment of Electronic Engineering, Fudan University, Shanghai, People's Republic of China.
Xiaojun ChenDepartment of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.
Guoqing WuDepartment of Electronic Engineering, Fudan University, Shanghai, People's Republic of China.
Xuefen LiuDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.
Peng ZhangDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China.
Yu BaiCenter for Child and Family Policy, Duke University, Durham, NC, USA.
Pengcong LuDepartment of Radiology, Yuyao People's Hospital, Ningbo, Zhejiang province, People's Republic of China.
Weigen YaoDepartment of Radiology, Yuyao People's Hospital, Ningbo, Zhejiang province, People's Republic of China.
Yuanyuan WangDepartment of Electronic Engineering, Fudan University, Shanghai, People's Republic of China.
Jinhua YuDepartment of Electronic Engineering, Fudan University, Shanghai, People's Republic of China. jhyu@fudan.edu.cn.
Guofu ZhangDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, People's Republic of China. guofuzh@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the ability of MRI radiomics to categorize ovarian masses and to determine the association between MRI radiomics and survival among ovarian epithelial cancer (OEC) patients.

methodA total of 286 patients with pathologically proven adnexal tumor were retrospectively included in this study. We evaluated diagnostic performance of the signatures derived from MRI radiomics in differentiating (1) between benign adnexal tumors and malignancies and (2) between type I and type II OEC. The least absolute shrinkage and selection operator method was used for radiomics feature selection. Risk scores were calculated from the Lasso model and were used for survival analysis.

resultFor the classification between benign and malignant masses, the MRI radiomics model achieved a high accuracy of 0.90 in the leave-one-out (LOO) cross-validation cohort and an accuracy of 0.87 in the independent validation cohort. For the classification between type I and type II subtypes, our method made a satisfactory classification in the LOO cross-validation cohort (accuracy = 0.93) and in the independent validation cohort (accuracy = 0.84). Low-high-high short-run high gray-level emphasis and low-low-high variance from coronal T2-weighted imaging (T2WI) and eccentricity from axial T1-weighted imaging (T1WI) images had the best performance in two classification tasks. The patients with higher risk scores were more likely to have poor prognosis (hazard ratio = 4.1694, p = 0.001).

conclusionOur results suggest radiomics features extracted from MRI are highly correlated with OEC classification and prognosis of patients. MRI radiomics can provide survival estimations with high accuracy. KEY POINTS: • The MRI radiomics model could achieve a higher accuracy in discriminating benign ovarian diseases from malignancies. • Low-high-high short-run high gray-level emphasis, low-low-high variance from coronal T2WI, and eccentricity from axial T1WI had the best performance outcomes in various classification tasks. • The ovarian cancer patients with high-risk scores had poor prognosis.

Indexed as

AdultAgedCohort StudiesDiagnosis, DifferentialFemaleFollow-Up StudiesHumansImage Interpretation, Computer-AssistedKaplan-Meier EstimateMagnetic Resonance ImagingMiddle AgedOvarian NeoplasmsPrognosisReproducibility of ResultsRetrospective StudiesROC CurveComputer-assisted diagnosisMagnetic resonance imagingOvarian epithelial cancerRadiomics

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.