Evidence map›Paper›PMID 30963255›Full record

ArticleJournal of neurology2019

Risk of traffic accidents after onset of vestibular disease assessed with a surrogate marker.

Doreen Huppert, Andreas Straube, Lucia Albers, Rüdiger von Kries, Viola Obermeier

Abstract read
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In one paragraph

Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Driving ability in patients with dizziness: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Doreen HuppertInstitute for Clinical Neurosciences and German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany. Doreen.Huppert@med.uni-muenchen.de.
Andreas StraubeDepartment of Neurology, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Lucia AlbersDivision of Epidemiology, Institute of Social Paediatrics and Adolescents Medicine, Ludwig-Maximilians-Universität München, Haydnstr. 5, 81377, Munich, Germany.
Rüdiger von KriesDivision of Epidemiology, Institute of Social Paediatrics and Adolescents Medicine, Ludwig-Maximilians-Universität München, Haydnstr. 5, 81377, Munich, Germany.
Viola ObermeierDivision of Epidemiology, Institute of Social Paediatrics and Adolescents Medicine, Ludwig-Maximilians-Universität München, Haydnstr. 5, 81377, Munich, Germany.

Funding

Bundesministerium für Bildung und Forschung 01 EO 0901Gemeinnützige Hertie-Stiftung Hertie-Stiftung
6 · The paper itself

Abstract

objectivesTo determine if the risk of traffic accidents increases after disease onset in patients with acute vestibular disorders. That could provide a valid rationale for guidelines on driving restrictions.

methods5,260,054 patient data (> 18 years of age) from a statutory health insurer were used to identify traffic injuries in incident cases of Menière's disease (MD) and vestibular neuritis (VN) in 2010-2013. Incident diagnoses were defined as the absence of such diagnoses in the preceding 5 years. Comparators were insured individuals with no such diagnoses throughout 2005-2017. The surrogate for traffic injuries were whiplash injuries coded in ICD-10 as diagnosis of sprain of ligaments of the cervical spine without structural changes.

resultsWe identified 4509 incident patients with Menière's disease and 25,448 with vestibular neuritis and 5,102,655 controls with no such diagnoses throughout the observation period. The incidence of traffic injuries was increased for both vestibular disorders prior to the time point of diagnosis-MD 0.72 [0.47; 0.97] and VN 0.66 [0.56; 0.76] compared to controls (0.46 [0.46; 0.47]). The temporal course of incidence in whiplash injuries showed no increase and was 0.64 [0.41; 0.88] for MD at diagnosis and 0.73 [0.48; 0.98] after diagnosis, for VN it was 0.81 [0.70; 0.92] at diagnosis and 0.65 [0.55; 0.74] after diagnosis.

conclusionsAlthough these data were not originally collected to address the research question, they provide a valid body of evidence. There is no rationale for driving restrictions, which substantially interfere with the individuals' quality of life, in patients with incident MD and VN.

Indexed as

Accidents, TrafficBiomarkersDatabases, FactualFemaleFollow-Up StudiesHumansMaleRisk FactorsVestibular DiseasesWhiplash InjuriesBiomarkersIncidence studyMenière’s diseaseTraffic accidentsVestibular diseaseVestibular neuritis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.