ArticleClinical research in cardiology : official journal of the German Cardiac Society2019
Does rhythm matter in acute heart failure? An insight from the British Society for Heart Failure National Audit.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 12 citations in OpenAlex.
- Quality of life after catheter and minimally invasive surgical ablation of paroxysmal and early persistent atrial fibrillation: results from the SCALAF trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Trial
- Timely and individualized heart failure management: need for implementation into the new guidelines.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Review
- Heart rate at discharge in patients with acute decompensated heart failure is a predictor of mortality.European journal of medical research · 2020Article
- Atrial inflammation in different atrial fibrillation subtypes and its relation with clinical risk factors.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- The year in cardiology: heart failure.European heart journal · 2020Article
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundAtrial fibrillation (AF) is the most common sustained arrhythmia in patients with acute heart failure (AHF). The presence of AF is associated with adverse prognosis in patients with chronic heart failure (CHF) but little is known about its impact in AHF.
methodsData were collected between April 2007 and March 2013 across 185 (> 95%) hospitals in England and Wales from patients with a primary death or a discharge diagnosis of AHF. We investigated the association between the presence of AF and all-cause mortality during the index hospital admission, at 30 days and 1 year post-discharge.
resultsOf 96,593 patients admitted with AHF, 44,642 (46%) were in sinus rhythm (SR) and 51,951 (54%) in AF. Patients with AF were older (mean age 79.8 (79.7-80) versus 74.7 (74.5-74.7) years; p < 0.001), than those in SR. In a multivariable analysis, AF was independently associated with mortality at all time points, in hospital (HR 1.15, 95% CI 1.09-1.21, p < 0.0001), 30 days (HR 1.13, 95% CI 1.08-1.19, p < 0.0001), and 1 year (HR 1.09, 95% CI 1.05-1.12, p < 0.0001). In subgroup analyses, AF was independently associated with worse 30-day outcome irrespective of sex, ventricular phenotype and in all age groups except in those aged between 55 and 74 years.
conclusionAF is independently associated with adverse prognosis in AHF during admission and up to 1 year post-discharge. As the clinical burden of concomitant AF and AHF increases, further refinement in the detection, treatment and prevention of AF-related complications may have a role in improving patient outcomes.
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