ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020
Detection of Influenza and Other Respiratory Viruses in Air Sampled From a University Campus: A Longitudinal Study.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Air Purifier Intervention for Respiratory Viral Exposure in Elementary Schools: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- Loss of Infectivity of Influenza Virus and SARS-CoV‑2 during Aerosol Sampling.Environmental science & technology letters · 2026Article
- Integrated monitoring of enveloped viruses in hospital environments: Detection, persistence, and implications for infection control.PloS one · 2026Article
- Controlled human influenza infection reveals heterogeneous expulsion of infectious virus into air.medRxiv : the preprint server for health sciences · 2025Article
- Interpretation of indoor air surveillance for respiratory infections: a prospective longitudinal observational study in a childcare setting.EBioMedicine · 2025Observational
- Indoor Air Quality Conditions and Respiratory Virus Detections in Elementary Schools-Kansas City, Missouri, February-March 2023.Indoor air · 2025Article
- Airborne Influenza Virus in Daycare Centers.Viruses · 2024Article
- The re-emergence of influenza following the COVID-19 pandemic in Victoria, Australia, 2021 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- SARS-CoV-2 and other airborne respiratory viruses in outdoor aerosols in three Swiss cities before and during the first wave of the COVID-19 pandemic.Environment international · 2022Article
- Indoor Air Quality including Respiratory Viruses.Toxics · 2021Article
- Transmissibility and transmission of respiratory viruses.Nature reviews. Microbiology · 2021Review
- Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant.Building and environment · 2021Article
- Evaluation of the exposure risk of SARS-CoV-2 in different hospital environment.Sustainable cities and society · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundRespiratory virus-laden particles are commonly detected in the exhaled breath of symptomatic patients or in air sampled from healthcare settings. However, the temporal relationship of detecting virus-laden particles at nonhealthcare locations vs surveillance data obtained by conventional means has not been fully assessed.
methodsFrom October 2016 to June 2018, air was sampled weekly from a university campus in Hong Kong. Viral genomes were detected and quantified by real-time reverse-transcription polymerase chain reaction. Logistic regression models were fitted to examine the adjusted odds ratios (aORs) of ecological and environmental factors associated with the detection of virus-laden airborne particles.
resultsInfluenza A (16.9% [117/694]) and influenza B (4.5% [31/694]) viruses were detected at higher frequencies in air than rhinovirus (2.2% [6/270]), respiratory syncytial virus (0.4% [1/270]), or human coronaviruses (0% [0/270]). Multivariate analyses showed that increased crowdedness (aOR, 2.3 [95% confidence interval {CI}, 1.5-3.8]; P < .001) and higher indoor temperature (aOR, 1.2 [95% CI, 1.1-1.3]; P < .001) were associated with detection of influenza airborne particles, but absolute humidity was not (aOR, 0.9 [95% CI, .7-1.1]; P = .213). Higher copies of influenza viral genome were detected from airborne particles >4 μm in spring and <1 μm in autumn. Influenza A(H3N2) and influenza B viruses that caused epidemics during the study period were detected in air prior to observing increased influenza activities in the community.
conclusionsAir sampling as a surveillance tool for monitoring influenza activity at public locations may provide early detection signals on influenza viruses that circulate in the community.
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