Evidence map›Paper›PMID 30963178›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

The Impact of Human Immunodeficiency Virus Exposure on Respiratory Syncytial Virus-associated Severe Respiratory Illness in South African Infants, 2011-2016.

Meredith L McMorrow, Stefano Tempia, Sibongile Walaza, Florette K Treurnicht, Jocelyn Moyes, Adam L Cohen, Marthi Pretorius, Orienka Hellferscee, Nicole Wolter, Anne von Gottberg and 7 more

Open access · greenAbstract readHistorical Article
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

Meredith L McMorrowInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Stefano TempiaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Sibongile WalazaCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Florette K TreurnichtCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Jocelyn MoyesCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Adam L CohenInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Marthi PretoriusCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Orienka HellfersceeCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Nicole WolterCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Anne von GottbergCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Arthemon NguwenezaCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Johanna M McAnerneyCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
Fathima NabyDepartment of Paediatrics, Pietermaritzburg Metropolitan Hospitals, University of KwaZulu-Natal.
Omphile MekgoeDepartment of Paediatrics, Klerksdorp Hospital, North West Province.
Marietjie VenterEmerging Vectorborne and Respiratory Virus Program, Center for Viral Zoonoses, Department of Medical Virology, University of Pretoria.
Shabir A MadhiMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, Johannesburg, South Africa.
Cheryl CohenCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
National Health Laboratory Service · ZACenters for Disease Control and Prevention · USEdendale Hospital · ZAUniversity of Pretoria · ZAUniversity of the Witwatersrand · ZA

Funding

Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09U01IP001048 · IP · NATIONAL HEALTH LABORATORY SERVICE · PI COHEN, CHERYL · 2016 to 2020
$19.9M
ACL HHS U01IP001048Intramural CDC HHS CC999999NCIRD CDC HHS U01 IP001048
6 · The paper itself

Abstract

From 2011 through 2016, we conducted surveillance for severe respiratory illness in infants. Human immunodeficiency virus exposure significantly increased the risk of respiratory syncytial virus (RSV)-associated hospitalization in infants aged <5 months. More than 60% of RSV-associated hospitalizations occurred in the first 4 months of life and may be preventable through maternal vaccination or birth-dose monoclonal antibody.

Indexed as

CoinfectionRespiratory Syncytial Virus, HumanFemaleHistory, 21st CenturyHIV InfectionsHospitalizationHumansInfantInfant, NewbornMaleMass ScreeningRespiratory Syncytial Virus InfectionsSeverity of Illness IndexSouth Africahuman immunodeficiency virusincidencerespiratory syncytial virusSouth Africa

Identifiers

PMID30963178
PMCPMC6934254
OpenAlexW2939379069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.