ArticleInternational journal of cardiology. Heart & vasculature2019
Impact of the clinical frailty scale on mid-term mortality in patients with ST-elevated myocardial infarction.
Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Association between frailty and depression in older adults with coronary heart disease: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Association between frailty and hypoproteinaemia in older patients: meta-analysis and systematic review.BMC geriatrics · 2024Pooled it
- Frailty scale with the best prediction of mortality in individuals diagnosed with acute coronary syndrome: systematic review and meta-analysis.Journal of geriatric cardiology : JGC · 2026Article
- Prediction Model for Frailty in Middle-Aged and Older Adults with Cardiovascular Disease.Vascular health and risk management · 2026Article
- Article
- Trends in antithrombotic therapy and clinical outcomes for percutaneous coronary intervention in Japan following the 2020 JCS guideline focused update: findings from the SAKURA PCI2 Antithrombotic Registry.Heart and vessels · 2025Article
- STEMI-OP in-hospital mortality prediction algorithms: Frailty-integrated machine learning in older patients undergoing primary PCI.npj aging · 2025Article
- Article
- Frailty prevalence, invasive treatment frequency, and in-hospital outcome in patients hospitalized for acute coronary syndrome in Germany (2005-2022): a nationwide registry study.The Lancet regional health. Europe · 2025Article
- Frailty as an independent predictor for midterm adverse outcomes in the elderly undergoing primary percutaneous coronary intervention: A longitudinal cohort study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Observational
- Use of machine learning algorithms to predict outcomes among frail patients undergoing percutaneous coronary intervention: Are we there yet?International journal of cardiology. Heart & vasculature · 2024Article
- Development and validation of frailty risk prediction model for elderly patients with coronary heart disease.BMC geriatrics · 2024Article
- Article
- Review
- Article
- Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis.World journal of clinical cases · 2024Article
- Comparison of the prognostic value of frailty assessment tools in patients aged ≥ 65 years hospitalized in a cardiac care unit with acute coronary syndrome.Journal of geriatric cardiology : JGC · 2022Article
- Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2022Review
- The Effect of Periprocedural Clinical Factors Related to the Course of STEMI in Men and Women Based on the National Registry of Invasive Cardiology Procedures (ORPKI) between 2014 and 2019.Journal of clinical medicine · 2021Article
- Frailty Scores and Their Utility in Older Patients with Cardiovascular Disease.Interventional cardiology (London, England) · 2021Review
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background"Frailty" is associated with poor prognosis in ST-elevated myocardial infarction (STEMI). However, there is little data regarding the impact of the Canadian Study of Health and Aging Clinical Frailty Scale (CFS), a simple and semiquantitative tool for assessing frailty, on mid-term mortality in STEMI patients.
methodsA total of 354 consecutive STEMI patients (mean age 69.8 ± 12.4 years; male 76.6%) who underwent percutaneous intervention between July 2014 and March 2017 were retrospectively reviewed. The study endpoint was mid-term mortality according to the CFS classification. Furthermore, in order to clarify the impact of CFS upon admission on mid-term mortality, the independent predictors of all-cause death were evaluated.
resultsPatients were categorized into three groups (CFS 1-3, n = 281; CFS 4-5, n = 62; and CFS 6-7, n = 11). During the study period (median 474 days), all-cause death was observed in 39 patients. After multivariate Cox regression analysis, higher CFS (adjusted hazard ratio [HR] 2.34, 95% confidence interval [CI] 1.43-3.85, p < 0.001), higher Killip score (adjusted HR 2.46, 95%CI 1.30-5.78, p = 0.002), and lower serum albumin level (adjusted HR 4.29, 95%CI 2.16-8.51, p < 0.001) were significantly associated with an increased risk of all-cause death.
conclusionIn conclusion, severe frailty was associated with mid-term mortality in STEMI patients who underwent PCI.
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