Evidence map›Paper›PMID 30963043›Full record

ReviewJournal of traditional and complementary medicine2019

The medical perspective of cupping therapy: Effects and mechanisms of action.

Abdullah M N Al-Bedah, Ibrahim S Elsubai, Naseem Akhtar Qureshi, Tamer Shaban Aboushanab, Gazzaffi I M Ali, Ahmed Tawfik El-Olemy, Asim A H Khalil, Mohamed K M Khalil, Meshari Saleh Alqaed

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of traditional and complementary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06689371 (Dry Needling Versus Dry Cupping on Pain and Disability in Cervicogenic Headache Patients), which is not on this map. Cited by 74 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06689371 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Dry Needling Versus Dry Cupping on Pain and Disability in Cervicogenic Headache Patients

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled45ConditionsDry Needling, Dry Cupping, Cervicogenic HeadacheArmsGroup A (Dry Needling), Group B (Dry cupping), Group C (control)
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  17. Enhanced localized pressure-mediated non-viral gene delivery.Drug delivery and translational research · 2025
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdullah M N Al-BedahNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Ibrahim S ElsubaiNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Naseem Akhtar QureshiNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Tamer Shaban AboushanabNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Gazzaffi I M AliNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Ahmed Tawfik El-OlemyNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Asim A H KhalilNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Mohamed K M KhalilNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.
Meshari Saleh AlqaedNational Center of Complementary and Alternative Medicine, Ministry of Health, Riyadh 11662, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cupping Therapy (CT) is an ancient method and currently used in the treatment of a broad range of medical conditions. Nonetheless the mechanism of action of (CT) is not fully understood. This review aimed to identify possible mechanisms of action of (CT) from modern medicine perspective and offer possible explanations of its effects. English literature in PubMed, Cochrane Library and Google Scholar was searched using key words. Only 223 articles identified, 149 records screened, and 74 articles excluded for irrelevancy. Only 75 full-text articles were assessed for eligibility, included studies in this review were 64. Six theories have been suggested to explain the effects produced by cupping therapy. Pain reduction and changes in biomechanical properties of the skin could be explained by "Pain-Gate Theory", "Diffuse Noxious Inhibitory Controls" and "Reflex zone theory". Muscle relaxation, changes in local tissue structures and increase in blood circulation might be explained by "Nitric Oxide theory". Immunological effects and hormonal adjustments might be attributed to "Activation of immune system theory". Releasing of toxins and removal of wastes and heavy metals might be explained by "Blood Detoxification Theory". These theories may overlap or work interchangeably to produce various therapeutic effects in specific ailments and diseases. Apparently, no single theory exists to explain the whole effects of cupping. Further researches are needed to support or refute the aforesaid theories, and also develop innovative conceptualizations of (CT) in future.

Indexed as

CuppingEffectsHijamaMechanisms of action

Identifiers

PMID30963043
PMCPMC6435947

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.