ArticleJournal of thoracic disease2019
Clinical characteristics and prognosis of ground-glass opacity nodules in young patients.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 21 citations in OpenAlex.
- Clinical characteristics of ground-glass opacities in young patients : a single-center retrospective study.Journal of cardiothoracic surgery · 2026Article
- A Clinical-Radiomics Nomogram for the Preoperative Prediction of Aggressive Micropapillary and a Solid Pattern in Lung Adenocarcinoma.Current oncology (Toronto, Ont.) · 2025Article
- Construction and validation of a risk stratification model based on Lung-RADSInsights into imaging · 2025Article
- The efficacy of the 4-hook needle localization for pulmonary ground glass nodules: a single-center retrospective analysis.Journal of cardiothoracic surgery · 2025Article
- Computed tomography-derived radiomics models for distinguishing difficult-to-diagnose inflammatory and malignant pulmonary nodules.Biomedical engineering and computational biology · 2025Article
- Different clinicopathological features between young and older patients with pulmonary adenocarcinoma and ground-glass opacity.Scientific reports · 2024Article
- Construction and validation of a risk score system for diagnosing invasive adenocarcinoma presenting as pulmonary pure ground-glass nodules: a multi-center cohort study in China.Quantitative imaging in medicine and surgery · 2024Article
- Discrimination of invasive lung adenocarcinoma from Lung-RADS category 2 nonsolid nodules through visual assessment: a retrospective study.European radiology · 2024Article
- Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Quantitative evaluation of density variability in the lesion-lung boundary zone to differentiate pulmonary subsolid nodules.Quantitative imaging in medicine and surgery · 2023Article
- CT-guided placement of microcoil end in the pleural cavity for video-assisted thoracic surgical resection of ground-glass opacity: a retrospective study.Journal of cardiothoracic surgery · 2022Article
- Clinical features and surgical outcomes of young patients with lung adenocarcinoma manifesting as ground glass opacity.Frontiers in oncology · 2022Article
- Predictors of Invasive Adenocarcinomas among Pure Ground-Glass Nodules Less Than 2 cm in Diameter.Cancers · 2021Article
- Comparison of Clinical and Pathological Characteristics Between Extremely Multiple GGNs and Single GGNs.Frontiers in oncology · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe detection rate of ground-glass opacity (GGO) in young patients has increased year by year with the increasingly widespread use of high-resolution computed tomography (HRCT) and the increased resolution of HRCT imaging. However, no scholars have reported the clinical characteristics and prognosis of GGO in young patients systematically. The purpose of this study is to investigate the clinical characteristics and prognosis presenting as GGO in young patients.
methodsClinical data of 127 young patients who were diagnosed as GGO and who underwent video-assisted thoracoscopic surgery (VATS) and had routine pathological examination were collected from January 2016 to January 2017. Nodules were classified according to benign and malignant: 26 benign nodules (Group A) and 115 malignant nodules (Group B). The pathological types, nodules size, surgical methods were analyzed, and the clinical characteristics and prognosis were evaluated.
resultsThe results of pathological examination of 91 pure ground-glass opacities (pGGOs) revealed 16 adenocarcinoma in situs (AISs), 42 micro invasive adenocarcinomas (MIAs), 13 invasive adenocarcinomas (IAs), 8 atypical adenomatous hyperplasias (AAHs), 1 inflammatory granuloma, 2 pulmonary inflammatory pseudotumors (IPTs) and 9 other benign nodules. The results of pathological examination of 50 mixed ground-glass opacities (mGGOs) revealed 6 AISs, 29 MIAs, 9 IAs, 1 AAH, 2 inflammatory granulomas and 3 other benign nodules. All patients had no lymph nodes invasion. The rates of perioperative complications were 6.30%, compared to 7.63% for long-term complications. None of the patients with GGO experienced a recurrence and death [2-year recurrence-free survival (RFS), 100%; 2-year overall survival (OS), 100%].
conclusionsThe GGO in young patients that received VATS has a high proportion of malignant, its prognosis is satisfied.
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