Evidence map›Paper›PMID 30962824›Full record

ArticleOpen access Macedonian journal of medical sciences2019

The Influence of Wharton Jelly Mesenchymal Stem Cell toward Matrix

Vivi Sofia, Ellyza Nasrul, Menkher Manjas, Gusti Revilla

Open access · diamondAbstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Wharton's jelly and osteoarthritis of the knee.British medical bulletin · 2024
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vivi SofiaPostgraduate Biomedical Science, Faculty of Medicine, Andalas University, Padang, Indonesia.
Ellyza NasrulDepartment of Clinical Pathology, Faculty of Medicine, Andalas University, Indonesia.
Menkher ManjasDepartment of Orthopedic Surgery, Faculty of Medicine, Andalas University, Indonesia.
Gusti RevillaDepartment of Anatomy, Faculty of Medicine, Andalas University, Indonesia.
Andalas University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTherapy for osteoarthritis (OA) with satisfactory results has not been found to date. In OA pathogenesis,

aimThis study aims to identify the influence of Wharton Jelly Mesenchymal Stem Cell (MSC-WJ) on MATERIAL AND

methodsThis research is pure experimental research. The sample used derived from synovial tissue of OA patients who underwent Total Knee Replacement (TKR) surgery. This study was divided into six groups treated with 4 replications. Group I and II (control groups) were synoviocyte of OA incubated for 24 and 48 hours, respectively. Group III and IV were MSC-WJ incubated for 24 and 48 hours, respectively. Group V and VI were Synoviocyte-MSC-WJ co-culture group incubated for 24 and 48 hours, respectively. Identification of

resultThe results showed that MSC-WJ reduced

conclusionThis study concluded that MSC-WJ in OA synoviocyte significantly reduced the expression of MMP-13 and

Indexed as

Co-cultureMatrix Metalloproteinase-13Mesenchymal Stem Cell Wharton JellyRELA

Identifiers

PMID30962824
PMCPMC6447349
OpenAlexW2916194269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.