Evidence map›Paper›PMID 30962822›Full record

ArticleBiotechnology for biofuels2019

Improving squalene production by enhancing the NADPH/NADP

Wen Xu, Jia Yao, Lijun Liu, Xi Ma, Wei Li, Xiaojing Sun, Yang Wang

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 53 citations in OpenAlex.

  1. Menaquinone biosynthesis inEngineering microbiology · 2026
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  11. Engineering peroxisomal biosynthetic pathways for maximization of triterpene production inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
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  19. Recent advances in the microbial production of squalene.World journal of microbiology & biotechnology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wen XuThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Jia YaoThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Lijun LiuThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Xi MaThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Wei LiThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Xiaojing SunThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Yang WangThe Molecular Virology and Viral Immunology Laboratory, Xi'an Medical University, Xi'an, 710021 Shaanxi China.
Xi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSqualene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial fermentation processes for squalene production have been emerging over recent years. In this study, to study the squalene-producing potential of

resultsHerein, human truncated squalene synthase was engineered in

conclusionsThis study provided novel strategies for improving squalene yield and demonstrated the potential of producing squalene by

Indexed as

Feeding module modificationMenaquinone pathwaypgiRate-limiting enzymesSqualeneUdhA

Identifiers

PMID30962822
PMCPMC6437923
OpenAlexW2972961160

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.