Evidence map›Paper›PMID 30962749›Full record

ArticleYonago acta medica2019

Effect of Cetuximab and

Naomi Miyake, Hiroki Chikumi, Kosuke Yamaguchi, Miyako Takata, Miki Takata, Kensaku Okada, Tsuyoshi Kitaura, Masaki Nakamoto, Akira Yamasaki

Open access · diamondAbstract read
In one paragraph

Article in Yonago acta medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Naomi MiyakeDivision of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Hiroki Chikumi†Division of Infectious Diseases, Tottori University Hospital, Yonago 683-8504, Japan.
Kosuke YamaguchiDivision of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Miyako Takata‡Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Miki TakataDivision of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Kensaku Okada†Division of Infectious Diseases, Tottori University Hospital, Yonago 683-8504, Japan.
Tsuyoshi Kitaura†Division of Infectious Diseases, Tottori University Hospital, Yonago 683-8504, Japan.
Masaki Nakamoto†Division of Infectious Diseases, Tottori University Hospital, Yonago 683-8504, Japan.
Akira YamasakiDivision of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
Tottori University · JPTottori University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe epidermal growth factor receptor (EGFR) is a therapeutic target for patients with non-small cell lung cancer (NSCLC). Cetuximab is an anti-EGFR monoclonal antibody that inhibits EGFR signaling and proliferation of colorectal cancer and head and neck cancers. Since only few NSCLC patients benefit from cetuximab therapy, we evaluated a novel combination treatment using cetuximab and

methodsAlterations in

resultsAll cell lines were harboring wild-type

conclusion

Indexed as

cetuximabEGFR siRNAKRASnon-small cell lung cancer

Identifiers

PMID30962749
PMCPMC6437414
OpenAlexW2923049617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.