Evidence map›Paper›PMID 30962543›Full record

ArticleEye (London, England)2019

Foveal and parafoveal choroidal thickness pattern measuring by swept source optical coherence tomography.

Pear Pongsachareonnont, Thanapong Somkijrungroj, Buravej Assavapongpaiboon, Theerada Chitamara, Maytavee Chuntarapas, Disorn Suwajanakorn

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Evaluation of the Choroid in Women with Uncomplicated Pregnancy.Translational vision science & technology · 2020
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Pear PongsachareonnontVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. pear.p@chulahospital.org.
Thanapong SomkijrungrojVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Buravej AssavapongpaiboonVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Theerada ChitamaraVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Maytavee ChuntarapasVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Disorn SuwajanakornVitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
King Chulalongkorn Memorial Hospital · THChulalongkorn University · THThai Red Cross Society · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the choroidal thickness (CT) in foveal and parafoveal regions in Thai adults using swept-source optical coherence tomography (SS-OCT).

methodsWe enrolled healthy volunteers ≥18 years of age from King Chulalongkorn Memorial Hospital, Thailand, during September 2015 to March 2016. Optical coherence tomography (OCT) of the macula was performed, and subfoveal CT was measured manually using a line scan. Average thicknesses of retinal and choroidal layers in regions of the Early Treatment Diabetic Retinopathy Study grid were measured automatically. A multivariate analysis was conducted to determine correlations between CTs in the foveal and parafoveal regions and retinal layers.

resultsAltogether, 144 eyes from 144 subjects (29 men, 115 women; mean age 41 years) were studied. The mean foveal CT was 282.4 ± 13.8 µm. It was thicker in the temporal fovea than in the nasal fovea (p < 0.001) and thicker in men than in women. Multivariate analysis showed that age and sex were significantly negatively correlated with the thickness of the retina, ganglion cell layer, outer retinal layer, and choroid but not of the nerve fiber layer. Regression analysis revealed that the CT decreased approximately 1.5 μm per year.

conclusionsAge and sex significantly influence choroidal thickness. Macular CT in a healthy eye thins with age. CT decreases with age faster at distances away from the foveal center than at the center. Subfoveal CT was greater than the mean CT. Parafoveal CT should be evaluated to identify specific retinal-choroidal disease.

Indexed as

Tomography, Optical CoherenceAdolescentAdultAge FactorsAxial Length, EyeChoroidCross-Sectional StudiesFemaleFovea CentralisHealthy VolunteersHumansMaleMiddle AgedOrgan SizeProspective StudiesReference Values

Identifiers

PMID30962543
PMCPMC7002508
OpenAlexW2929505716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.