ArticleNature communications2019
RNA editing is abundant and correlates with task performance in a social bumblebee.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 80 citations in OpenAlex.
- The neuronal A-to-I RNA editome of Solenopsis invicta expands conserved recoding repertoire between two ant species.BMC genomics · 2026Article
- RNA-seq variants reveal distinct patterns in the aging epitranscriptome: an in-depth analysis of age-matched Alzheimer's Disease patients and a cognitively normal cohort.bioRxiv : the preprint server for biology · 2026Article
- Molecular Phylogeny of "Chemosensory Proteins" in Bacteria and Arthropods: CSP as an Extremely Ancient Gene.Journal of molecular evolution · 2026Article
- Different mRNAs encoding identical proteins: how and why?Journal of applied genetics · 2026Article
- Fascination with RNA Editing: In the Lights of Evolution and Biology.Journal of molecular evolution · 2025Review
- Signal peptides restrict genome evolution and A-to-I RNA editing.NAR genomics and bioinformatics · 2025Article
- Morphological Comparisons of Adult Worker Bees Developed in Chinese and Italian Honey Bee Combs.Insects · 2025Article
- Adaptive evolution of A-to-I auto-editing site in Adar of eusocial insects.BMC genomics · 2024Article
- Comparative genomic analyses on assassin bugiScience · 2024Article
- The first A-to-I RNA editome of hemipteran species Coridius chinensis reveals overrepresented recoding and prevalent intron editing in early-diverging insects.Cellular and molecular life sciences : CMLS · 2024Article
- Article
- An orthology-based methodology as a complementary approach to retrieve evolutionarily conserved A-to-I RNA editing sites.RNA biology · 2024Article
- Identification and Interpretation of A-to-I RNA Editing Events in Insect Transcriptomes.International journal of molecular sciences · 2023Review
- Article
- Autorecoding A-to-I RNA editing sites in theRNA (New York, N.Y.) · 2023Article
- Lactobacillus for ribosome peptide editing cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Review
- Expression of subunits of an insecticide target receptor varies across tissues, life stages, castes, and species of social bees.Molecular ecology · 2023Article
- A full repertoire of Hemiptera genomes reveals a multi-step evolutionary trajectory of auto-RNA editing site in insectRNA biology · 2023Article
- Squid express conserved ADAR orthologs that possess novel features.Frontiers in genome editing · 2023Article
- Unveiling the functional and evolutionary landscape of RNA editing in chicken using genomics and transcriptomics.Zoological research · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colonies of the bumblebee Bombus terrestris are characterized by wide phenotypic variability among genetically similar full-sister workers, suggesting a major role for epigenetic processes. Here, we report a high level of ADAR-mediated RNA editing in the bumblebee, despite the lack of an ADAR1-homolog. We identify 1.15 million unique genomic sites, and 164 recoding sites residing in 100 protein coding genes, including ion channels, transporters, and receptors predicted to affect brain function and behavior. Some edited sites are similarly edited in other insects, cephalopods and even mammals. The global editing level of protein coding and non-coding transcripts weakly correlates with task performance (brood care vs. foraging), but not affected by dominance rank or juvenile hormone known to influence physiology and behavior. Taken together, our findings show that brain editing levels are high in naturally behaving bees, and may be regulated by relatively short-term effects associated with brood care or foraging activities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.