Evidence map›Paper›PMID 30962378›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Prediction and identification of recurrent genomic rearrangements that generate chimeric chromosomes in

Kim Palacios-Flores, Alejandra Castillo, Carina Uribe, Jair García Sotelo, Margareta Boege, Guillermo Dávila, Margarita Flores, Rafael Palacios, Lucia Morales

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kim Palacios-FloresLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0002-3308-2714
Alejandra CastilloLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0003-4581-9549
Carina UribeLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0002-2361-8618
Jair García SoteloLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0002-9462-2737
Margareta BoegeLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0002-4924-8504
Guillermo DávilaLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0002-9343-3133
Margarita FloresLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México.ORCID 0000-0003-0310-094X
Rafael PalaciosLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México palacios@liigh.unam.mx lmorales@liigh.unam.mx.ORCID 0000-0003-0078-9526
Lucia MoralesLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Juriquilla, Querétaro 76230, México palacios@liigh.unam.mx lmorales@liigh.unam.mx.ORCID 0000-0002-9511-5067

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomes are dynamic structures. Different mechanisms participate in the generation of genomic rearrangements. One of them is nonallelic homologous recombination (NAHR). This rearrangement is generated by recombination between pairs of repeated sequences with high identity. We analyzed rearrangements mediated by repeated sequences located in different chromosomes. Such rearrangements generate chimeric chromosomes. Potential rearrangements were predicted by localizing interchromosomal identical repeated sequences along the nuclear genome of the

Indexed as

Chromosomes, FungalGene RearrangementGenome, FungalGenomicsModels, GeneticPolymerase Chain ReactionRepetitive Sequences, Nucleic AcidSaccharomyces cerevisiaeSequence Analysis, DNAchimeric chromosomesgenome architecturegenomic rearrangementsPMGL strategyreciprocal translocations

Identifiers

PMID30962378
PMCPMC6486755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.