Evidence map›Paper›PMID 30962354›Full record

ArticleJournal of bacteriology2019

Proteomic Analysis of the Pseudomonas aeruginosa Iron Starvation Response Reveals PrrF Small Regulatory RNA-Dependent Iron Regulation of Twitching Motility, Amino Acid Metabolism, and Zinc Homeostasis Proteins.

Cassandra E Nelson, Weiliang Huang, Luke K Brewer, Angela T Nguyen, Maureen A Kane, Angela Wilks, Amanda G Oglesby-Sherrouse

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Journal of bacteriology · 2026
    Article
  5. Metal-independent effects of calprotectin on cocultures ofbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Microbiology (Reading, England) · 2026
    Article
  8. Article
  9. Calprotectin protectsmSystems · 2025
    Article
  10. Vancomycin Sensitization inACS infectious diseases · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Quantitative proteomic analysis reveals Ga(III) polypyridyl catecholate complexes disrupt Aspergillus fumigatus mitochondrial function.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  17. Article
  18. Frontiers in molecular biosciences · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cassandra E Nelson *Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA.
Weiliang Huang *Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA.
Luke K BrewerDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA.
Angela T NguyenDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA.
Maureen A KaneDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA mkane@rx.umaryland.edu awilks@rx.umaryland.edu aoglesby@rx.umaryland.edu.
Angela WilksDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA mkane@rx.umaryland.edu awilks@rx.umaryland.edu aoglesby@rx.umaryland.edu.
Amanda G Oglesby-SherrouseDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland, USA mkane@rx.umaryland.edu awilks@rx.umaryland.edu aoglesby@rx.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
Graduate Training at The Chemistry Biology InterfaceT32GM066706 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L, SMITH, AARON T · 2004 to 2023
$3.3M
Mechanistic characterization and regulation of the non-redundant phu and has heme uptake systems of Pseudomonas aeruginosaR01AI134886 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Angela Wilks · 2018 to 2026
$3.0M
Metallobiochemistry of innate immunity and bacterial physiologyR01GM126376 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M, OGLESBY, AMANDA GAIL · 2017 to 2024
$2.4M
Role of PrrF and PrrH regulation in Pseudomonas aeruginosa pathogenesisR01AI123320 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI OGLESBY, AMANDA GAIL · 2016 to 2020
$2.2M
Molecular determinants of retinoid metabolism in embryonic tissuesR01HD077260 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI KANE, MAUREEN A, MOISE, ALEX RADU · 2014 to 2018
$1.6M
NIAID NIH HHS R01 AI123320NIAID NIH HHS R01 AI134886NIAID NIH HHS T32 AI095190NICHD NIH HHS R01 HD077260NIGMS NIH HHS R01 GM126376NIGMS NIH HHS T32 GM066706
6 · The paper itself

Abstract

Iron is a critical nutrient for most microbial pathogens, and the immune system exploits this requirement by sequestering iron. The opportunistic pathogen

Indexed as

Amino AcidsBacterial ProteinsGene Expression Regulation, BacterialHomeostasisIronProteomicsPseudomonas aeruginosaRNA, BacterialZincAmino AcidsBacterial ProteinsIronRNA, BacterialZincironPrrFPseudomonas aeruginosasmall RNAstwitching motility

Identifiers

PMID30962354
PMCPMC6531625
OpenAlexW2931056090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.