ArticleJournal of immunology (Baltimore, Md. : 1950)2019
Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery.
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In one paragraph
Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Nur77 agonism invigorates Natural Killer cell immunity against hepatocellular carcinoma.Nature communications · 2026Article
- Biophysical trade-offs in antibody evolution are resolved by conformation-mediated epistasis.bioRxiv : the preprint server for biology · 2026Article
- Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants.Open biology · 2024Article
- Nur77 protects the bladder urothelium from intracellular bacterial infection.Nature communications · 2024Article
- Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow.Nature communications · 2024Article
- Lipopolysaccharide-responsive beige-like anchor is involved in regulating NF-κB activation in B cells.Frontiers in immunology · 2024Article
- Article
- Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.Cell reports · 2023Article
- Enhanced protein synthesis is a defining requirement for neonatal B cell development.Frontiers in immunology · 2023Article
- IgD shapes the pre-immune naïve B cell compartment in humans.Frontiers in immunology · 2023Article
- GPR174 signals via GProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression.Cell reports · 2022Article
- NR4A family members regulate T cell tolerance to preserve immune homeostasis and suppress autoimmunity.JCI insight · 2021Article
- Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production.Science advances · 2021Article
- Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- NR4A1 Deletion in Marginal Zone B Cells Exacerbates Atherosclerosis in Mice-Brief Report.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
- NR4As apply brakes on the B cell response.Nature immunology · 2020Article
- NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting.Nature immunology · 2020Article
- Article
- Cross-Reactivity with Self-Antigen Tunes the Functional Potential of Naive B Cells Specific for Foreign Antigens.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Corey TanBiomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143.ORCID 0000-0002-5696-6766
James L MuellerDivision of Rheumatology, Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143.
Mark NoviskiBiomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143.
John HuizarHoward Hughes Medical Institute Medical Fellows Program, University of California, San Francisco, San Francisco, CA 94143.
Denise LauKnapp Center for Lupus and Immunology, Section of Rheumatology, Department of Medicine, The University of Chicago, Chicago, IL 60637.
Alexandra DubininDepartment of Laboratory Medicine, University of California, San Francisco, CA 94143.
Ari MolofskyDepartment of Laboratory Medicine, University of California, San Francisco, CA 94143.
Patrick C WilsonKnapp Center for Lupus and Immunology, Section of Rheumatology, Department of Medicine, The University of Chicago, Chicago, IL 60637.
Julie ZikhermanDivision of Rheumatology, Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143; julie.zikherman@ucsf.edu.ORCID 0000-0002-0873-192X
University of California, San Francisco · USUniversity of Chicago · USHoward Hughes Medical Institute · US
Funding
Toward a Universal Influenza Virus VaccineP01AI097092 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PALESE, PETER · 2012 to 2022
$17.6MINTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7MMOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0MDissecting unique functions of IgM and IgD BCRs in tolerance and autoimmunityR01AR069520 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZIKHERMAN, JULIE · 2016 to 2020
$1.7MTitrating CD45 expression in mice to study development of T cell toleranceK08AR059723 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZIKHERMAN, JULIE · 2010 to 2014
$598kHoward Hughes Medical InstituteNIAID NIH HHS P01 AI097092NIAID NIH HHS T32 AI007090NIAID NIH HHS T32 AI007334NIAMS NIH HHS K08 AR059723NIAMS NIH HHS R01 AR069520
Abstract
Nur77 (
Indexed as
AnimalsAntigensB-LymphocytesCell SurvivalImmune ToleranceMiceMice, KnockoutNuclear Receptor Subfamily 4, Group A, Member 1Proto-Oncogene Proteins B-rafReceptors, Antigen, B-CellAntigensBraf protein, mouseNr4a1 protein, mouseNuclear Receptor Subfamily 4, Group A, Member 1Proto-Oncogene Proteins B-rafReceptors, Antigen, B-Cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.