Evidence map›Paper›PMID 30962283›Full record

ArticleThe Journal of biological chemistry2019

H

Mei-Kuang Chen, Yi Du, Linlin Sun, Jennifer L Hsu, Yu-Han Wang, Yuan Gao, Jiaxing Huang, Mien-Chie Hung

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Cancer Cells Haploinsufficient for ATM Are Sensitized to PARP Inhibitors byInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 3 countries.

Mei-Kuang ChenThe University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.
Yi DuDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.
Linlin SunDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jennifer L HsuDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030.
Yu-Han WangDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 402, Taiwan.
Yuan GaoDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Jiaxing HuangDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Department of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Mien-Chie HungThe University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 402, Taiwan; Center of Molecular Medicine, China Medical University, Taichung 402, Taiwan. Electronic address: mhung@mail.cmu.edu.tw.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Rational Combination Therapy with PARP Inhibitors in Triple Negative Breast CancerR01CA211615 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YANG, LIUQING · 2017 to 2021
$2.1M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA211615
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are cellular by-products produced from metabolism and also anticancer agents, such as ionizing irradiation and chemotherapy drugs. The ROS H

Indexed as

Active Transport, Cell NucleusBreast NeoplasmsCell Line, TumorCell MembraneCell NucleusCoatomer ProteinDNA DamageDNA RepairFemaleHumansHydrogen PeroxideProto-Oncogene Proteins c-metSEC Translocation ChannelsSignal TransductionCoatomer ProteinCOPG1 protein, humanHydrogen PeroxideMET protein, humanProto-Oncogene Proteins c-metSEC61B protein, humanSEC Translocation Channelsbreast cancerc-METhepatocyte growth factor receptor (HGFR)hydrogen peroxidenuclear transportnucleusreactive oxygen species (ROS)receptor tyrosine kinasevesicle trafficking

Identifiers

PMID30962283
PMCPMC6544865
OpenAlexW2936397900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.