Evidence map›Paper›PMID 30962219›Full record

ArticleDiabetes2019

Genetic Variation Within the

Özkan Aydemir, Janelle A Noble, Jeffrey A Bailey, Åke Lernmark, Patrick Marsh, Agnes Andersson Svärd, Frank Bearoff, Elizabeth P Blankenhorn, John P Mordes, Better Diabetes Diagnosis (BDD) Study Group

Open access · greenAbstract read
In one paragraph

Article in Diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Özkan AydemirDivision of Transfusion Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.
Janelle A NobleChildren's Hospital Oakland Research Institute, Oakland, CA.
Jeffrey A BaileyDivision of Transfusion Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.
Åke LernmarkDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital, Malmö, Sweden.
Patrick MarshDivision of Transfusion Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.
Agnes Andersson SvärdDepartment of Clinical Sciences, Lund University/CRC, Skåne University Hospital, Malmö, Sweden.
Frank BearoffDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA.
Elizabeth P BlankenhornDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA.
John P MordesDivision of Endocrinology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA john.mordes@umassmed.edu.ORCID 0000-0003-2414-380X
Better Diabetes Diagnosis (BDD) Study Group
University of Massachusetts Chan Medical School · USDrexel University · USLund University · SE

Funding

Type 1 Diabetes Genetics ConsortiumU01DK062418 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RICH, STEPHEN S. · 2002 to 2007
$59.8M
NIDDK NIH HHS U01 DK062418
6 · The paper itself

Abstract

Type 1 diabetes (T1D) involves the interaction of multiple gene variants, environmental factors, and immunoregulatory dysfunction. Major T1D genetic risk loci encode HLA-DR and -DQ. Genetic heterogeneity and linkage disequilibrium in the highly polymorphic HLA region confound attempts to identify additional T1D susceptibility loci. To minimize HLA heterogeneity, T1D patients (

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAllelesCase-Control StudiesDiabetes Mellitus, Type 1FemaleGene FrequencyGenetic VariationGenotypeHLA-DR3 AntigenHLA-DR alpha-ChainsHomozygoteHumansIntronsMaleHLA-DR3 AntigenHLA-DR alpha-Chains

Identifiers

PMID30962219
PMCPMC6609989
OpenAlexW2935729650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.