Evidence map›Paper›PMID 30961639›Full record

ArticleParasites & vectors2019

Comparative cost-effectiveness of immunoassays and FLOTAC for diagnosing Giardia spp. infection in dogs.

Paola Pepe, Davide Ianniello, Leucio Camara Alves, Maria Elena Morgoglione, Maria Paola Maurelli, Antonio Bosco, Giuseppe Cringoli, Laura Rinaldi

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Parasitosis in Pet Dogs from Rondônia, Amazon Biome, and Human Perception of Zoonoses.International journal of environmental research and public health · 2024
    Article
  2. Article
  3. Article
  4. Effectiveness of Fenbendazole and Metronidazole AgainstFrontiers in veterinary science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paola PepeDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Davide IannielloDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Leucio Camara AlvesDepartment of Veterinary Medicine, Federal Rural University of Pernambuco, R. Manuel de Medeiros s/n, Dois Irmãos, Recife, PE, 52171-900, Brazil. leucioalves@gmail.com.
Maria Elena MorgoglioneDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Maria Paola MaurelliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Antonio BoscoDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Giuseppe CringoliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.
Laura RinaldiDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, CREMOPAR, Campania Region, Eboli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiardia spp. is a protozoan pathogen and is the most common enteric parasite of domestic animals and humans. Assays for detecting infection in fecal samples using direct or indirect examinations are important tools for diagnosing the disease. The objective of the present study was to compare the cost-effectiveness of immunoassays and FLOTAC technique for diagnosing Giardia spp. infection in dogs.

resultsFecal samples from 80 positive stray dogs were tested for the presence of copro-antigens of Giardia spp. using the direct immunofluorescence assay (IFA), a rapid enzyme-linked immunosorbent assay (ELISA) and the FLOTAC double technique. All methods were performed in accordance with the instructions reported in the original description for each technique. The results showed that ELISA can be run in less time than IFA and almost at the same time of the FLOTAC technique. Among the tests used in this study, FLOTAC had the lowest cost per correct diagnosis, compared with immunoassays.

conclusionsThe results from this cost-effectiveness analysis, in combination with the sensitivity and specificity of the FLOTAC technique, suggest that the FLOTAC technique can be use in the routine diagnosis of Giardia spp. infection in dogs.

Indexed as

AnimalsCost-Benefit AnalysisDog DiseasesDogsEnzyme-Linked Immunosorbent AssayFecesFluorescent Antibody Technique, DirectGiardiasisSensitivity and SpecificityZinc SulfateZinc SulfateDiagnosisFLOTACGiardia spp.Immunoassays

Identifiers

PMID30961639
PMCPMC6454601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.