ArticleBiomedical engineering online2019
Continuous distraction osteogenesis device with MAAC controller for mandibular reconstruction applications.
Article in Biomedical engineering online, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review).Molecular medicine reports · 2026Review
- A Real-Time Mechanical Information Acquisition System and Finite Element Prediction Method for Limb Lengthening: A Pilot In Vivo Study.Sensors (Basel, Switzerland) · 2026Article
- Hybrid Distractor for Continuous Mandibular Distraction Osteogenesis.Bioengineering (Basel, Switzerland) · 2022Article
- Experimental validation of finite element simulation of a new custom-designed fixation plate to treat mandibular angle fracture.Biomedical engineering online · 2021Article
- The RNA Methyltransferase METTL3 Promotes Endothelial Progenitor Cell Angiogenesis in Mandibular Distraction Osteogenesis via the PI3K/AKT Pathway.Frontiers in cell and developmental biology · 2021Article
- Real-Time Wireless Platform for In Vivo Monitoring of Bone Regeneration.Sensors (Basel, Switzerland) · 2020Article
- Review of automatic continuous distraction osteogenesis devices for mandibular reconstruction applications.Biomedical engineering online · 2020Review
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistraction osteogenesis (DO) is a novel technique widely used in human body reconstruction. DO has got a significant role in maxillofacial reconstruction applications (MRA); through this method, bone defects and skeletal deformities in various cranio-maxillofacial areas could be reconstructed with superior results in comparison to conventional methods. Recent studies revealed in a DO solution, using an automatic continuous distractor could significantly improve the results while decreasing the existing issues. This study is aimed at designing and developing a novel automatic continuous distraction osteogenesis (ACDO) device to be used in the MRA.
methodsThe design is comprised of a lead screw translation mechanism and a stepper motor, placed outside of the mouth to generate the desired continuous linear force. This externally generated and controlled distraction force (DF) is transferred into the moving bone segment via a flexible miniature transition system. The system is also equipped with an extra-oral ACDO controller, to generate an accurate, reliable, and stable continuous DF.
resultsSimulation and experimental results have justified the controller outputs and the desired accuracy of the device. Experiments have been conducted on a sheep jaw bone and results have showed that the developed device could offer a continuous DF of 38 N with distraction accuracy of 7.6 nm on the bone segment, while reducing the distraction time span.
conclusionContinuous DF with high resolution positioning control, along with the smaller size of the distractor placed in the oral cavity will help in improving the result of the reconstruction operation and leading to a successful DO procedure in a shorter time period. The developed ACDO device has less than 1% positioning error while generating sufficient DF. These features make this device a suitable distractor for an enhanced DO treatment in MRA.
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