Evidence map›Paper›PMID 30961585›Full record

ArticleBMC medical informatics and decision making2019

Evidential MACE prediction of acute coronary syndrome using electronic health records.

Danqing Hu, Wei Dong, Xudong Lu, Huilong Duan, Kunlun He, Zhengxing Huang

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Danqing HuCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Key Lab for Biomedical Engineering of Ministry of Education, Zheda Road, Hangzhou, China.
Wei DongDepartment of Cardiology, Chinese PLA General Hospital, Fuxing Road, Beijing, China.
Xudong LuCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Key Lab for Biomedical Engineering of Ministry of Education, Zheda Road, Hangzhou, China.
Huilong DuanCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Key Lab for Biomedical Engineering of Ministry of Education, Zheda Road, Hangzhou, China.
Kunlun HeDepartment of Cardiology, Chinese PLA General Hospital, Fuxing Road, Beijing, China. HEKL301@aliyun.com.
Zhengxing HuangCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Key Lab for Biomedical Engineering of Ministry of Education, Zheda Road, Hangzhou, China. zhengxinghuang@zju.edu.cn.
Zhejiang University · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor adverse cardiac event (MACE) prediction plays a key role in providing efficient and effective treatment strategies for patients with acute coronary syndrome (ACS) during their hospitalizations. Existing prediction models have limitations to cope with imprecise and ambiguous clinical information such that clinicians cannot reach to reliable MACE prediction results for individuals.

methodsTo remedy it, this study proposes a hybrid method using Rough Set Theory (RST) and Dempster-Shafer Theory (DST) of evidence. In details, four state-of-the-art models, including one traditional ACS risk scoring model, i.e., GRACE, and three machine learning based models, i.e., Support Vector Machine, L

resultsHaving applied the proposed method on a clinical dataset consisting of 2930 ACS patient samples, our model achieves 0.715 AUC value with competitive standard deviation, which is the best prediction results comparing with the four single base models and two baseline ensemble models.

conclusionsFacing with the limitations in traditional ACS risk scoring models, machine learning models and the uncertainties of EHR data, we present an ensemble approach via RST and DST to alleviate this problem. The experimental results reveal that our proposed method achieves better performance for the problem of MACE prediction when compared with the single models.

Indexed as

Electronic Health RecordsMachine LearningAcute Coronary SyndromeHospitalizationHumansLogistic ModelsPredictive Value of TestsPrognosisRisk Assessment

Identifiers

PMID30961585
PMCPMC6454666
OpenAlexW2939631812

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.