Evidence map›Paper›PMID 30961354›Full record

ArticleChronic respiratory disease

Health-care utilization and expenditures among patients with comorbid bronchiectasis and chronic obstructive pulmonary disease in US clinical practice.

Frederic Douglas Seifer, Gary Hansen, Derek Weycker

Open access · goldAbstract read
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. A systematic literature review of the clinical and socioeconomic burden of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
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  12. Prevalence of bronchiectasis: a narrative review.Therapeutic advances in respiratory disease
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Frederic Douglas Seifer1 St. Lawrence Health System, Potsdam, NY, USA.
Gary Hansen2 RespirTech, St. Paul, MN, USA.
Derek Weycker3 Policy Analysis Inc. (PAI), Brookline, MA, USA.ORCID 0000-0002-5405-2215
Policy Analysis (United States) · USSt. Lawrence University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research suggests that bronchiectasis (BE) may be more common than previously believed and that comorbid chronic obstructive pulmonary disease (COPD) is widespread in this patient population. Little is known about the economic burden among patients with BE, and less is known about the burden among those with comorbid BE + COPD. A retrospective matched-cohort design and data from a US health-care claims repository were employed. From the source population comprising adults who had comprehensive medical/drug benefits for ≥1 day in 2013 (i.e. the referent year) and evidence of BE and/or COPD at any time from 2009 to 2013, patients with BE + COPD were age/sex-matched (1:1:1) to patients with BE only and patients with COPD only. For each matched subgroup, annualized levels of respiratory-related and all-cause health-care utilization and expenditures in 2013 were summarized. Source population included 679,679 patients; among those with BE ( n = 31,027), 50% had comorbid COPD. Mean (95% CI) annual levels of respiratory-related utilization and expenditures among matched patients with BE + COPD ( n = 11,685) were higher by 2.4-3.5 times versus patients with BE only and 2.0-2.5 times versus patients with COPD only: hospitalizations, 0.39 (0.37-0.41) versus 0.11 (0.09-0.12) and 0.16 (0.14-0.17); ambulatory encounters, 16.5 (16.1-16.9) versus 6.8 (6.6-7.0) and 8.2 (7.9-8.4); and total expenditures, US$15,685 (14,693-16,678) versus US$5605 (5059-6150) and US$6262 (5655-6868). Respiratory-related utilization and expenditures are high among patients with BE or COPD receiving medical care in US clinical practice and are especially high among those with comorbid BE + COPD receiving medical care, emphasizing the importance of identifying and treating this unique patient population. Funding for this research was provided by RespirTech to Policy Analysis Inc. (PAI).

Indexed as

Health ExpendituresAdolescentAdultAgedAged, 80 and overAmbulatory CareBronchiectasisCohort StudiesComorbidityFemaleHealth ServicesHospitalizationHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveBronchiectasischronic obstructivecosts and cost analysiseconomicshealth expenditurespulmonary disease

Identifiers

PMID30961354
PMCPMC6456842
OpenAlexW2937614158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.