Evidence map›Paper›PMID 30961122›Full record

ReviewPolymers2018

Bioreactor Operating Strategies for Improved Polyhydroxyalkanoate (PHA) Productivity.

Warren Blunt, David B Levin, Nazim Cicek

Abstract readReview
In one paragraph

Review in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Advances in Polyhydroxyalkanoate (PHA) Production, Volume 3.Bioengineering (Basel, Switzerland) · 2022
    Article
  7. Potential use ofAIMS microbiology · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Rheological Behavior of High Cell DensityBioengineering (Basel, Switzerland) · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Warren BluntDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, MB R3T 5V6, Canada. umbluntw@myumanitoba.ca.
David B LevinDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, MB R3T 5V6, Canada. david.levin@umanitoba.ca.
Nazim CicekDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, MB R3T 5V6, Canada. nazim.cicek@umanitoba.ca.ORCID 0000-0002-3929-2536

Funding

Genome Canada FiCoGenNatural Sciences and Engineering Research Council of Canada RGPIN-5916-2016
6 · The paper itself

Abstract

Microbial polyhydroxyalkanoates (PHAs) are promising biodegradable polymers that may alleviate some of the environmental burden of petroleum-derived polymers. The requirements for carbon substrates and energy for bioreactor operations are major factors contributing to the high production costs and environmental impact of PHAs. Improving the process productivity is an important aspect of cost reduction, which has been attempted using a variety of fed-batch, continuous, and semi-continuous bioreactor systems, with variable results. The purpose of this review is to summarize the bioreactor operations targeting high PHA productivity using pure cultures. The highest volumetric PHA productivity was reported more than 20 years ago for poly(3-hydroxybutryate) (PHB) production from sucrose (5.1 g L

Indexed as

bioreactorcontinuous fermentationfed-batch fermentationPHAspolyhydroxyalkanoatesproductivityscale-up

Identifiers

PMID30961122
PMCPMC6290639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.