Evidence map›Paper›PMID 30961118›Full record

ArticlePolymers2018

An RGD-Containing Peptide Derived from Wild Silkworm Silk Fibroin Promotes Cell Adhesion and Spreading.

Zhao Kang, Yining Wang, Jingjing Xu, Guangzhou Song, Mengyao Ding, Huanrong Zhao, Jiannan Wang

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
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  8. Article
  9. Article
  10. Review
  11. Silk fibroin nanoscaffolds for neural tissue engineering.Journal of materials science. Materials in medicine · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhao KangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. 20165215005@stu.suda.edu.cn.
Yining WangDepartment of Biological Sciences, Xi'an Jiaotong-Liverpool University, No. 111 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. ywy960119@163.com.
Jingjing XuNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. 20185215004@stu.suda.edu.cn.
Guangzhou SongNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. 20185215032@stu.suda.edu.cn.
Mengyao DingNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. 20185215066@stu.suda.edu.cn.
Huanrong ZhaoNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. zhaohuanrong1211@126.com.
Jiannan WangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, No. 199 Ren-ai Road, Suzhou Industrial Park, Suzhou 215123, China. wangjn@suda.edu.cn.
Soochow University · CNXi’an Jiaotong-Liverpool University · CN

Funding

National Natural Science Foundation of China 51473108National Natural Science Foundation of China 51873141
6 · The paper itself

Abstract

Arginine-Glycine-Aspartate (RGD) tripeptide can promote cell adhesion when present in the amino acid of proteins such as fibronectin. In order to demonstrate the bioactivity of an RGD-containing silk protein, a gene encoding the RGD motif-containing peptide GSGAGGRGDGGYGSGSS (⁻RGD⁻) derived from nonmulberry silk was designed and cloned, then multimerised and inserted into a commercial pGEX expression vector for recombinant expression of (⁻RGD⁻)

Indexed as

biosynthesiscell adhesioncell proliferationRGD peptidessilk fibroinwild silkworm

Identifiers

PMID30961118
PMCPMC6290608
OpenAlexW2898244640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.