Evidence map›Paper›PMID 30960922›Full record

ReviewPolymers2018

Hydrogel Biomaterials for Stem Cell Microencapsulation.

Goeun Choe, Junha Park, Hansoo Park, Jae Young Lee

Abstract readReview
In one paragraph

Review in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Goeun ChoeSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea. ch70005@gist.ac.kr.
Junha ParkSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea. jpjh0451@gist.ac.kr.
Hansoo ParkSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Korea. heyshoo@cau.ac.kr.
Jae Young LeeSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea. jaeyounglee@gist.ac.kr.ORCID 0000-0003-4493-2494

Funding

Gwangju Institute of Science and Technology GRIKorea Health Industry Development Institute HI14C3484
6 · The paper itself

Abstract

Stem cell transplantation has been recognized as a promising strategy to induce the regeneration of injured and diseased tissues and sustain therapeutic molecules for prolonged periods in vivo. However, stem cell-based therapy is often ineffective due to low survival, poor engraftment, and a lack of site-specificity. Hydrogels can offer several advantages as cell delivery vehicles, including cell stabilization and the provision of tissue-like environments with specific cellular signals; however, the administration of bulk hydrogels is still not appropriate to obtain safe and effective outcomes. Hence, stem cell encapsulation in uniform micro-sized hydrogels and their transplantation in vivo have recently garnered great attention for minimally invasive administration and the enhancement of therapeutic activities of the transplanted stem cells. Several important methods for stem cell microencapsulation are described in this review. In addition, various natural and synthetic polymers, which have been employed for the microencapsulation of stem cells, are reviewed in this article.

Indexed as

hydrogelmicroencapsulationstem celltissue engineering

Identifiers

PMID30960922
PMCPMC6403586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.