Evidence map›Paper›PMID 30960737›Full record

ArticlePolymers2018

Preparation of Nafion/Polycation Layer-by-Layer Films for Adsorption and Release of Insulin.

Kentaro Yoshida, Katsuhiko Sato, Tetsuya Ono, Takenori Dairaku, Yoshitomo Kashiwagi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Nafion-Based Nanocarriers for Fluorine Magnetic Resonance Imaging.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kentaro YoshidaSchool of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan. k-yoshida@pha.ohu-u.ac.jp.
Katsuhiko SatoGraduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan. satok@m.tohoku.ac.jp.ORCID 0000-0002-8139-2880
Tetsuya OnoSchool of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan. t-ono@pha.ohu-u.ac.jp.
Takenori DairakuSchool of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan. t-dairaku@pha.ohu-u.ac.jp.
Yoshitomo KashiwagiSchool of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan. y-kashiwagi@pha.ohu-u.ac.jp.

Funding

Japan Society for the Promotion of Science 16K08189Japan Society for the Promotion of Science 18K06791
6 · The paper itself

Abstract

Thin films were prepared using layer-by-layer (LbL) deposition of Nafion (NAF) and polycations such as poly(allylamine hydrochloride) (PAH), poly(ethyleneimine) (PEI), and poly(diallydimethylammonium chloride) (PDDA). Insulin was then adsorbed on the NAF-polycation LbL films by immersion in an insulin solution. The NAF-polycation LbL films were characterized using a quartz crystal microbalance and an atomic force microscope. The release of insulin from the LbL films was characterized using UV-visible adsorption spectroscopy and fluorescence emission spectroscopy. The greatest amount of insulin was adsorbed on the NAF-PAH LbL film. The amount of insulin adsorbed on the (NAF/PAH)₅NAF LbL films by immersion in a 1 mg mL

Indexed as

controlled releasedrug deliveryinsulinlayer-by-layer filmNafion

Identifiers

PMID30960737
PMCPMC6403611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.