ReviewPolymers2018
Polysiloxanes in Theranostics and Drug Delivery: A Review.
Review in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Most Important Biomedical and Pharmaceutical Applications of Silicones.Materials (Basel, Switzerland) · 2025Review
- Small structural changes in siloxane-based lipidoids improve tissue-specific mRNA delivery.Nature nanotechnology · 2025Article
- Computer-Assisted Strategies as a Tool for Designing Green Monomer-Based Molecularly Imprinted Materials.International journal of molecular sciences · 2024Review
- Application of Silicone in Ophthalmology: A Review.Materials (Basel, Switzerland) · 2024Review
- The Nanostructured Self-Assembly and Thermoresponsiveness in Water of Amphiphilic Copolymers Carrying Oligoethylene Glycol and Polysiloxane Side Chains.Pharmaceutics · 2023Article
- Enhanced Tensile Properties, Biostability, and Biocompatibility of Siloxane-Cross-Linked Polyurethane Containing Ordered Hard Segments for Durable Implant Application.Molecules (Basel, Switzerland) · 2023Article
- Novel Silicone-Grafted Alginate as a Drug Delivery Scaffold: Pharmaceutical Characterization of Gliclazide-Loaded Silicone-Based Composite Microcapsules.Pharmaceutics · 2023Article
- A Fusion of Molecular Imprinting Technology and Siloxane Chemistry: A Way to Advanced Hybrid Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023Review
- Silicone Materials for Flexible Optoelectronic Devices.Materials (Basel, Switzerland) · 2022Review
- Influence of Addition of Antibiotics on Chemical and Surface Properties of Sol-Gel Coatings.Materials (Basel, Switzerland) · 2022Article
- The Influence of Self-Heating Iron on the Thermal, Mechanical, and Swelling Properties of PDMS Composites for Organic Solvents Removal.Polymers · 2021Article
- Effect of crosslinking on the physicochemical properties of polydimethylsiloxane-based levonorgestrel intrauterine systems.International journal of pharmaceutics · 2021Article
- Mechanical properties of bulk Sylgard 184 and its extension with silicone oil.Scientific reports · 2021Article
- Silane Modification of Mesoporous Materials for the Optimization of Antiviral Drug Adsorption and Release Capabilities in Vaginal Media.Pharmaceutics · 2021Article
- Micellar Carriers of Active Substances Based on Amphiphilic PEG/PDMS Heterograft Copolymers: Synthesis and Biological Evaluation of Safe Use on Skin.International journal of molecular sciences · 2021Article
- Development of Non-Porous Silica Nanoparticles towards Cancer Photo-Theranostics.Biomedicines · 2021Review
- Silicon-Containing Polymeric Materials.Polymers · 2021Article
- Metal Organic Framework@Polysilsesequioxane Core/Shell-Structured Nanoplatform for Drug Delivery.Pharmaceutics · 2020Article
- Article
- Drug Release of Hybrid Materials Containing Fe(II)Citrate Synthesized by Sol-Gel Technique.Materials (Basel, Switzerland) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the historical problems of medicine is that often, diagnosis and therapy do not interface, at best. Moreover, especially in some areas, such as oncology, the stress for the organism during the two phases (diagnosis and therapy) can become excessive, and be fatal to the success of the treatment. The extraordinary progress of nanotechnology in the last 25 years has offered the opportunity to build a nanoplatform able to ferry drugs, and loads onto them both imaging and therapeutic functions, thus creating nanosystems capable of diagnosis, drug delivery, and monitoring of therapeutic response. The purpose of this unusual, and up to recent times, unimaginable, marriage between diagnosis and therapeutics is the reaching of protocols more specific to individuals. The dual use of particles/device lead to a personalized medicine. Due to their biocompatibility, versatility, physical and chemical resistance, and ability to be functionalized, silica nanoparticles and polysiloxanes are the heart and the shield of this nanoplatform, respectively. In this short review, I analyze the applications of these silicon-based materials in the field of controlled drug delivery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.