ReviewPolymers2019
Macro- and Microphase Separated Protein-Polyelectrolyte Complexes: Design Parameters and Current Progress.
Review in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Effect of Polymer Structure on the Thermodynamics of Polyelectrolyte Complex Micelle Formation.Macromolecules · 2026Article
- Self-Assembled (Nano)Structures of Human Serum Albumin with Thermoresponsive Chitosan-Polymers · 2026Article
- Macromolecular dimensions of a synthetic polyelectrolyte as a factor in its interactions with protein and cells: desirability for longer chains.Journal of materials chemistry. B · 2026Article
- Rational Design of Zwitterionic Polymers with Tunable Phase Separation Propensity.Macromolecules · 2025Article
- Cationic Amino Acid Identity and Net Charge Influence Condensate Properties inBiomacromolecules · 2025Article
- Exploring the effects of excipients on complex coacervation.Journal of colloid and interface science · 2025Article
- Smart coacervate microdroplets: biomimetic design, material innovations, and emerging applications in biomacromolecule delivery.Bioactive materials · 2025Review
- Engineering Protein-Polyelectrolyte Interactions for Cellular Applications.Annual review of chemical and biomolecular engineering · 2025Review
- Protein-polyelectrolyte complexation: effects of sterically repulsive groups, macromolecular architecture and hierarchical assembly.Soft matter · 2025Article
- Form Equals Function: Influence of Coacervate Architecture on Drug Delivery Applications.ACS biomaterials science & engineering · 2024Review
- Polymers for Disrupting Protein-Protein Interactions: Where Are We and Where Should We Be?Biomacromolecules · 2024Review
- Harnessing polyelectrolyte complexes for precision cancer targeting: a comprehensive review.Medical oncology (Northwood, London, England) · 2024Review
- Article
- Structure and Dynamics of Hybrid Colloid-Polyelectrolyte Coacervates: Insights from Molecular Simulations.Macromolecules · 2023Article
- Polyelectrolyte Complexes from Oppositely Charged Filamentous Viruses.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Supramolecular Protein-Polyelectrolyte Assembly at Near Physiological Conditions-Water Proton NMR, ITC, and DLS Study.Molecules (Basel, Switzerland) · 2022Article
- Functional enzyme-polymer complexes.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Physical Property Scaling Relationships for Polyelectrolyte Complex Micelles.Macromolecules · 2021Article
- Advances in the Structural Design of Polyelectrolyte Complex Micelles.The journal of physical chemistry. B · 2021Article
- Dynamic Coupling in Unentangled Liquid Coacervates Formed by Oppositely Charged Polyelectrolytes.Macromolecules · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein-containing polyelectrolyte complexes (PECs) are a diverse class of materials, composed of two or more oppositely charged polyelectrolytes that condense and phase separate near overall charge neutrality. Such phase-separation can take on a variety of morphologies from macrophase separated liquid condensates, to solid precipitates, to monodispersed spherical micelles. In this review, we present an overview of recent advances in protein-containing PECs, with an overall goal of defining relevant design parameters for macro- and microphase separated PECs. For both classes of PECs, the influence of protein characteristics, such as surface charge and patchiness, co-polyelectrolyte characteristics, such as charge density and structure, and overall solution characteristics, such as salt concentration and pH, are considered. After overall design features are established, potential applications in food processing, biosensing, drug delivery, and protein purification are discussed and recent characterization techniques for protein-containing PECs are highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.