Evidence map›Paper›PMID 30960485›Full record

ArticlePolymers2019

Controlled Electron-Beam Synthesis of Transparent Hydrogels for Drug Delivery Applications.

Sarah Glass, Mathias Kühnert, Bernd Abel, Agnes Schulze

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Radiation-Induced Hydrogel for Water Treatment.Gels (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah GlassLeibniz Institute of Surface Engineering (IOM), Permoserstraße 15, D-04318 Leipzig, Germany. sarah.glass@iom-leipzig.de.
Mathias KühnertLeibniz Institute of Surface Engineering (IOM), Permoserstraße 15, D-04318 Leipzig, Germany. mathias.kuehnert@iom-leipzig.de.
Bernd AbelLeibniz Institute of Surface Engineering (IOM), Permoserstraße 15, D-04318 Leipzig, Germany. bernd.abel@iom-leipzig.de.
Agnes SchulzeLeibniz Institute of Surface Engineering (IOM), Permoserstraße 15, D-04318 Leipzig, Germany. agnes.schulze@iom-leipzig.de.ORCID 0000-0003-1316-1367
Leibniz Institute of Surface Engineering · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we highlight hydrogels prepared by electron-beam polymerization. In general, the electron-beam-polymerized hydrogels showed improved mechanical and optical transmittances compared to the conventional UV-cured hydrogels. They were more elastic and had a higher crosslinking density. Additionally, they were transparent over a broader wavelength range. The dependence of the mechanical and optical properties of the hydrogels on the number of single differential and total irradiation doses was analyzed in detail. The hydrogels were prepared for usage as a drug delivery material with methylene blue as a drug model. In the first set of experiments, methylene blue was loaded reversibly after the hydrogel synthesis. Electron-beam-polymerized hydrogels incorporated twice as much methylene blue compared to the UV-polymerized gels. Furthermore, the release of the model drug was found to depend on the crosslinking degree of the hydrogels. In addition, electron-beam polymerization enabled the irreversible binding of the drug molecules if they were mixed with monomers before polymerization.

Indexed as

crosslinking degreedrug deliveryelectron beamhydrogelsPEDGApolymerization

Identifiers

PMID30960485
PMCPMC6473313
OpenAlexW2921476318

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.