Evidence map›Paper›PMID 30960408›Full record

ArticlePolymers2019

Design and Fabrication by Thermal Imprint Lithography and Mechanical Characterization of a Ring-Based PDMS Soft Probe for Sensing and Actuating Forces in Biological Systems.

Tommaso Dattoma, Antonio Qualtieri, Gianmichele Epifani, Massimo De Vittorio, Francesco Rizzi

Abstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tommaso DattomaCenter for Bio-Molecular Nanotechnologies@Unile, Istituto Italiano di Tecnologia, Via Eugenio Barsanti 14, 73010 Arnesano (LE), Italy. tommaso.dattoma.1984@gmail.com.
Antonio QualtieriCenter for Bio-Molecular Nanotechnologies@Unile, Istituto Italiano di Tecnologia, Via Eugenio Barsanti 14, 73010 Arnesano (LE), Italy. antonio.qualtieri@iit.it.ORCID 0000-0002-2207-8111
Gianmichele EpifaniIstituto di Nanotecnologia, Consiglio Nazionale delle Ricerche, 73100 Lecce, Italy. gianmichele.epifani@nanotec.cnr.it.
Massimo De VittorioCenter for Bio-Molecular Nanotechnologies@Unile, Istituto Italiano di Tecnologia, Via Eugenio Barsanti 14, 73010 Arnesano (LE), Italy. massimo.devittorio@iit.it.
Francesco RizziCenter for Bio-Molecular Nanotechnologies@Unile, Istituto Italiano di Tecnologia, Via Eugenio Barsanti 14, 73010 Arnesano (LE), Italy. francesco.rizzi@iit.it.ORCID 0000-0002-5142-5231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, the design, fabrication and mechanical characterization of a novel polydimethylsiloxane (PDMS) soft probe for delivering and sensing forces in biological systems is proposed. On the basis of preliminary finite element (FEM) analysis, the design takes advantage of a suitable core geometry, characterized by a variable spring-like ring. The compliance of probes can be finely set in a wide range to measure forces in the micronewton to nanonewton range. In particular, this is accomplished by properly resizing the ring geometry and/or exploiting the mixing ratio-based elastic properties of PDMS. Fabrication by the thermal imprint lithography method allows fast and accurate tuning of ring sizes and tailoring of the contact section to their targets. By only varying geometrical parameters, the stiffness ranges from 1080 mNm

Indexed as

force sensorhair cellmechanosensingPDMSsoft probethermal imprint lithography

Identifiers

PMID30960408
PMCPMC6473920

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.