Fabrication and Application of Dual-Modality Polymer Nanoparticles Based on an Aggregation-Induced Emission-Active Fluorescent Molecule and Magnetic Fe₃O₄.

Lingyun Wang, Meiying Huang, Hao Tang, Derong Cao, Yu Zhao

Open access · goldAbstract read

In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 58% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Polymeric dual-modal imaging nanoprobe with two-photon aggregation-induced emission for fluorescence imaging and gadolinium-chelation for magnetic resonance imaging.Bioactive materials · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lingyun WangSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. lingyun@scut.edu.cn.

Meiying HuangSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. hmy_1015@126.com.

Hao TangSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. haotang@scut.edu.cn.

Derong CaoSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. drcao@scut.edu.cn.

Yu ZhaoShanghai Key Laboratory of Magnetic Resonance and Department of Physics, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China. zhaoyu2013022063@163.com.

South China University of Technology · CNEast China Normal University · CN

Funding

Natural Science Foundation of Guangdong Province 2015A030313209, 2016A030311034

6 · The paper itself

Abstract

Fluorescent magnetic nanoparticles (NPs) utilized for imaging hold great promise for biomedical applications, but it remains a challenging task. Here, we report novel dual-modality NPs using an aggregation-induced emission (AIE)-active and near-infrared (NIR) emissive dye (TPAS) and magnetic Fe₃O₄ as the core, and biocompatible polymer Pluronic F-127 as the encapsulation matrix by self-assembly procedures. The obtained fluorescent-magnetic AIE NPs have both high fluorescence quantum yield (13.8%) at 700 nm and high magnetic saturation value. With good photostability and biocompatibility, the resulting NPs show effective MRI ability, but also a stain in cytoplasm with a strong NIR fluorescent signal.

Indexed as

AIEbioimagingdual-modalityMRI

Identifiers

PMID30960204

DOI10.3390/polym11020220

PMCPMC6419270

OpenAlexW2912059510

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.