Evidence map›Paper›PMID 30959983›Full record

ArticleMolecules (Basel, Switzerland)2019

Effects of Carbazole Derivatives on Neurite Outgrowth and Hydrogen Peroxide-Induced Cytotoxicity in Neuro2a Cells.

Yoshiko Furukawa, Atsushi Sawamoto, Mizuki Yamaoka, Makiko Nakaya, Yuhzo Hieda, Tominari Choshi, Noriyuki Hatae, Satoshi Okuyama, Mitsunari Nakajima, Satoshi Hibino

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Total synthesis of pyrrolo[2,3-Beilstein journal of organic chemistry · 2021
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yoshiko FurukawaDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. furukawa@g.matsuyama-u.ac.jp.ORCID 0000-0003-1233-3526
Atsushi SawamotoDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. asawamot@g.matsuyama-u.ac.jp.
Mizuki YamaokaDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. 16131209@matsuyama-u.ac.jp.
Makiko NakayaDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. mu.yakuri.015@gmail.com.
Yuhzo HiedaFaculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen-cho, Fukuyama, Hiroshima 729-0292, Japan. hieda@fukuyama-u.ac.jp.
Tominari ChoshiFaculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen-cho, Fukuyama, Hiroshima 729-0292, Japan. choshi@fukuyama-u.ac.jp.
Noriyuki HataeSchool of Pharmaceutical Sciences, Health Science University of Hokkaido, Ishikari, Tobetsu, Hokkaido 061-0293, Japan. nhatae@hoku-iryo-u.ac.jp.ORCID 0000-0001-8249-964X
Satoshi OkuyamaDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. sokuyama@g.matsuyama-u.ac.jp.
Mitsunari NakajimaDepartment of Pharmaceutical Pharmacology, College of Pharmaceutical Sciences, Matsuyama University, 4-2 Bunkyo-cho, Matsuyama, Ehime 790-8578, Japan. mnakajim@g.matsuyama-u.ac.jp.
Satoshi HibinoFaculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 1 Sanzo, Gakuen-cho, Fukuyama, Hiroshima 729-0292, Japan. satoshihibino@ma.ccnw.ne.jp.
Matsuyama University · JPFukuyama University · JPHealth Sciences University of Hokkaido · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have demonstrated that oxidative stress plays an important role in several ailments including neurodegenerative diseases and cerebral ischemic injury. Previously we synthesized some carbazole compounds that have anti-oxidant ability in vitro. In this present study, we found that one of these 22 carbazole compounds, compound

Indexed as

AnimalsCarbazolesCell DifferentiationCell SurvivalHydrogen PeroxideMolecular StructureNeuronal OutgrowthNeuronsSignal TransductioncarbazoleCarbazolesHydrogen Peroxideanti-oxidantcarbazoleneurite outgrowthneuro2a cellsneuronal death

Identifiers

PMID30959983
PMCPMC6479671
OpenAlexW2927597110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.