Evidence map›Paper›PMID 30959906›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Polyphenolic Composition of

Efthalia Kerasioti, Anna Apostolou, Ioannis Kafantaris, Konstantinos Chronis, Eleana Kokka, Christina Dimitriadou, Evangelia N Tzanetou, Alexandros Priftis, Sofia D Koulocheri, Serkos A Haroutounian and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 61 citations in OpenAlex.

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  7. Nutrients · 2025
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  10. Kinetic Modeling and Biological Activities ofAntioxidants (Basel, Switzerland) · 2025
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  11. Infrared Laser-Assisted Extraction of Bioactive Compounds fromInternational journal of molecular sciences · 2025
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  14. Astragalin fromAntioxidants (Basel, Switzerland) · 2024
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  19. Article
  20. Antioxidant and Antimicrobial Properties of Selected Fruit Juices.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Efthalia KerasiotiDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. e-f-thalia@hotmail.com.
Anna ApostolouLaboratory of Nutritional Physiology and Feeding, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece. annapost21@msn.com.
Ioannis KafantarisDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. kafantarisioannis@gmail.com.
Konstantinos ChronisDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. kochronis@uth.gr.
Eleana KokkaDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. elkokka@uth.gr.
Christina DimitriadouDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. xristina_211@hotmail.com.
Evangelia N TzanetouLaboratory of Nutritional Physiology and Feeding, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece. eyatza@gmail.com.
Alexandros PriftisDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. priftis@uth.gr.
Sofia D KoulocheriLaboratory of Nutritional Physiology and Feeding, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece. skoul@aua.gr.
Serkos A HaroutounianLaboratory of Nutritional Physiology and Feeding, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece. sehar@aua.gr.
Demetrios KouretasDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. dkouret@uth.gr.
Dimitrios StagosDepartment of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. stagkos@med.uth.gr.
University of Thessaly · GRAgricultural University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was the investigation of the antioxidant activity of plant extracts from Rosa canina, Rosa sempervivens and Pyrocantha coccinea. The results showed that the bioactive compounds found at higher concentrations were in the R. canina extract: hyperoside, astragalin, rutin, (+)-catechin and (-)-epicatechin; in the R. sempervirens extract: quinic acid, (+)-catechin, (-)-epicatechin, astragalin and hyperoside; and in the P. coccinea extract: hyperoside, rutin, (-)-epicatechin, (+)-catechin, astragalin, vanillin, syringic acid and chlorogenic acid. The total polyphenolic content was 290.00, 267.67 and 226.93 mg Gallic Acid Equivalent (GAE)/g dw, and the total flavonoid content 118.56, 65.78 and 99.16 mg Catechin Equivalent (CE)/g dw for R. caninna, R. sempervirens and P. coccinea extracts, respectively. The extracts exhibited radical scavenging activity in DPPH and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS)•⁺ assays and protection from ROO•-induced DNA damage in the following potency order: R. canina > R. sempervirens > P. coccinea. Finally, treatment with R. canina and P. coccinea extract significantly increased the levels of the antioxidant molecule glutathione, while R. canina extract significantly decreased Reactive Oxygen Species (ROS) in endothelial cells. The results herein indicated that the R. canina extract in particular may be used for developing food supplements or biofunctional foods for the prevention of oxidative stress-induced pathological conditions of endothelium.

Indexed as

antioxidantsendothelial cellsglutathionepolyphenolsPyrocantha coccineaRosa caninaRosa sempervivens

Identifiers

PMID30959906
PMCPMC6523071
OpenAlexW2931523745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.