Evidence map›Paper›PMID 30959839›Full record

ReviewCancers2019

Cerebral Thromboembolism after Lobectomy for Lung Cancer: Pathological Diagnosis and Mechanism of Thrombus Formation.

Hirotsugu Hashimoto, Genki Usui, Yuta Tsugeno, Keisuke Sugita, Gulanbar Amori, Teppei Morikawa, Kentaro Inamura

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The pulmonary-vascular-stump filling defect on CT post lung tumor resection: a predictor of cancer progression.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Dual-VENC 4D Flow MRI Can Detect Abnormal Blood Flow in the Left Atrium That Potentially Causes Thrombosis Formation after Left Upper Lobectomy.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hirotsugu HashimotoDepartment of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo 141-8625, Japan. hhashimoto-tki@umin.ac.jp.ORCID 0000-0002-1455-4974
Genki UsuiDepartment of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo 141-8625, Japan. gusui-tky@umin.ac.jp.
Yuta TsugenoDivision of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan. yuta.tsugeno@jfcr.or.jp.
Keisuke SugitaDepartment of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan. keisuke.integralugita@gmail.com.
Gulanbar AmoriDivision of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan. obulhasim.gulanbar@jfcr.or.jp.
Teppei MorikawaDepartment of Diagnostic Pathology, NTT Medical Center Tokyo, Tokyo 141-8625, Japan. tmorikawa-tky@umin.ac.jp.
Kentaro InamuraDivision of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan. kentaro.inamura@jfcr.or.jp.ORCID 0000-0001-6444-3861
NTT Medical Center · JPJapanese Foundation For Cancer Research · JPTokyo Medical and Dental University · JP

Funding

JSPS KAKENHI JP16K08679JSPS KAKENHI JP18K15103
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide. Although molecular therapies have emerged as efficacious strategies for the treatment of lung cancer, surgical resection is still recommended as a radical therapeutic option. Currently, lobectomy is regarded as the most reliable radical treatment of primary lung cancer. Among the various complications after lobectomy, cerebral thromboembolism requires attention as a life-threatening complication during the early postoperative period. It occurs in 0.2⁻1.2% of surgical cases of lung cancer and typically develops following left upper lobectomy with a long pulmonary vein stump (PVS). PVS-associated thrombosis is known to cause cerebral thromboembolism after such procedures; however, distinguishing this specific complication from that caused by postoperative atrial fibrillation is challenging. We summarize herein the diagnostic pathology of thrombus formation in accordance with its thrombogenic mechanism. We focus on the potential utility of the pathological assessment of thrombectomy specimens. The morphological information obtained from these specimens enables the presumption of thrombogenic etiology and provides useful clues to both select an appropriate pharmacotherapy and determine a follow-up treatment for cerebral thromboembolism.

Indexed as

cerebral thromboembolismlobectomylung cancerpathologythrombus

Identifiers

PMID30959839
PMCPMC6521235
OpenAlexW2934930979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.