ArticleInternational journal of molecular sciences2019
Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
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Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
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Who cites it
27 citing papers in PubMed, 37 citations in OpenAlex.
- Unfolded Protein Response Pathways in Cancer: Mechanisms, Tumor Biology and Therapeutic Opportunities.Molecular diagnosis & therapy · 2026Review
- Sustained intravitreal delivery of carnosic acid by RADA16 peptide hydrogel protects the retina in acute ocular hypertension.Scientific reports · 2026Article
- Neuroprotective role of NRF2 activation against ER Stress-Mediated apoptosis in obstructive sleep apnea.The Journal of biological chemistry · 2026Article
- Nerve growth factor: what can surgeons and oncologists learn from a neurological and psychological biomarker?Molecular medicine (Cambridge, Mass.) · 2025Review
- Nrf2 Activation and Antioxidant Properties of Chromone-Containing MTDLs for Alzheimer's Disease Treatment.Molecules (Basel, Switzerland) · 2025Article
- Novel potential neuroprotective targets for DengZhanXiXin injection in middle cerebral artery occlusion rats recommended by quantitative proteomics and simulated docking.Frontiers in neuroscience · 2025Article
- SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway.Cell stress & chaperones · 2023Review
- Natural Drugs: A New Direction for the Prevention and Treatment of Diabetes.Molecules (Basel, Switzerland) · 2023Review
- Neuroprotective Effects of Carnosic Acid: Insight into Its Mechanisms of Action.Molecules (Basel, Switzerland) · 2023Review
- Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4).Journal of immunology research · 2023Article
- PGM3 inhibition shows cooperative effects with erastin inducing pancreatic cancer cell deathFrontiers in oncology · 2023Article
- The integrated stress response is activated in the salivary glands of Sjögren's syndrome patients.Frontiers in medicine · 2023Article
- Article
- Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives.Pharmaceutics · 2022Review
- HepaticNutrients · 2021Article
- The Role of AKR1B10 in Physiology and Pathophysiology.Metabolites · 2021Review
- Phytochemicals as Regulators of Genes Involved in Synucleinopathies.Biomolecules · 2021Review
- Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug ofAntioxidants (Basel, Switzerland) · 2021Article
- The Impact of Endoplasmic Reticulum-Associated Protein Modifications, Folding and Degradation on Lung Structure and Function.Frontiers in physiology · 2021Review
- JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.FEBS open bio · 2020Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Junsei MimuraDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. jmimura@hirosaki-u.ac.jp.
Atsushi Inose-MaruyamaDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. ainose@tohoku-mpu.ac.jp.
Shusuke TaniuchiDivision of Molecular Biology, Institute of Advanced Medical Sciences, The University of Tokushima, Tokushima 770-8503, Japan. taniuchi@genome.tokushima-u.ac.jp.
Kunio KosakaResearch and Development Center, Nagase & Co. Ltd., Kobe 651-2241, Japan. kunio.kosaka@nagase.co.jp.
Hidemi YoshidaDepartment of Vascular Biology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. hidemi_yoshida@gakushikai.jp.
Hiromi YamazakiDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. hiromi-y@hirosaki-u.ac.jp.
Shuya KasaiDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. kasai-s@hirosaki-u.ac.jp.
Nobuhiko HaradaDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. nharada@med.tohoku.ac.jp.
Randal J KaufmanDegenerative Diseases Research Program, Sanford Burnham Prebys Medical Discovery Research Institute, La Jolla, CA 92037, USA. rkaufman@sbpdiscovery.org.
Seiichi OyadomariDivision of Molecular Biology, Institute of Advanced Medical Sciences, The University of Tokushima, Tokushima 770-8503, Japan. oyadomar@genome.tokushima-u.ac.jp.
Ken ItohDepartment of Stress Response Science, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan. itohk@hirosaki-u.ac.jp.
Hirosaki University · JPTokushima University · JPDiscovery Institute · USNagase ChemteX (Japan) · JP
Funding
"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"R01AG062190 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI HUANG, TIMOTHY YIKAI, KAUFMAN, RANDAL J. · 2019 to 2023
$4.8MNovel roles for the Alzheimer's Disease (AD) risk gene, SORLA in neuroprotection in ADR01AG061875 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI HUANG, TIMOTHY YIKAI · 2018 to 2022
$3.4MMechanism of ER Protein Misfolding-Induced Mitochondrial DysfunctionR01DK113171 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2017 to 2020
$2.5MAlteration in protein interactions with proinsulin and insulin in type 2 diabetesR24DK093074 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2011 to 2011
$518kMinistry of Education, Culture, Sports, Science and Technology 26111010NIA NIH HHS R01 AG061875NIA NIH HHS R01 AG062190NIDDK NIH HHS R01 DK113171NIDDK NIH HHS R24 DK093074NIH HHS CA198103NIH HHS DK042394NIH HHS DK110973
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene Expression RegulationAbietanesActivating Transcription Factor 4Aldehyde ReductaseAldo-Keto ReductasesAntioxidantsCell Line, TumorCytoprotectionGene Expression Regulation, NeoplasticHumansHydroquinonesModels, BiologicalNerve Growth FactorNF-E2-Related Factor 2Signal TransductionStress, Physiological2-tert-butylhydroquinoneAbietanesActivating Transcription Factor 4AKR1B10 protein, humanAldehyde ReductaseAldo-Keto ReductasesAntioxidantsHydroquinonesNerve Growth FactorNF-E2-Related Factor 2NGF protein, humansalvinTunicamycinAntioxidantATF4Carnosic acidNGFNrf2
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.