Evidence map›Paper›PMID 30959793›Full record

ArticleInternational journal of molecular sciences2019

Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler's Murine Encephalomyelitis.

Florian Hansmann, Ning Zhang, Vanessa Herder, Eva Leitzen, Wolfgang Baumgärtner

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Florian HansmannDepartment of Pathology, University of Veterinary Medicine Hannover; Center for Systems Neuroscience 30559 Hannover, Germany. Florian.Hansmann@tiho-hannover.de.ORCID 0000-0001-6064-7728
Ning ZhangDepartment of Pathology, University of Veterinary Medicine Hannover; Center for Systems Neuroscience 30559 Hannover, Germany. zhangning1111@126.com.
Vanessa HerderDepartment of Pathology, University of Veterinary Medicine Hannover; Center for Systems Neuroscience 30559 Hannover, Germany. Vanessa.Herder@tiho-hannover.de.
Eva LeitzenDepartment of Pathology, University of Veterinary Medicine Hannover; Center for Systems Neuroscience 30559 Hannover, Germany. Eva.Leitzen@tiho-hannover.de.
Wolfgang BaumgärtnerDepartment of Pathology, University of Veterinary Medicine Hannover; Center for Systems Neuroscience 30559 Hannover, Germany. Wolfgang.Baumgaertner@tiho-hannover.de.
University of Veterinary Medicine Hannover, Foundation · DE

Funding

Niedersachsen-Research Network on Neuroinfectiology (N-RENNT) of the Ministry of Science and Culture of Lower Saxony N/A
6 · The paper itself

Abstract

Theiler's murine encephalomyelitis (TME) represents a versatile animal model for studying the pathogenesis of demyelinating diseases such as multiple sclerosis. Hallmarks of TME are demyelination, astrogliosis, as well as inflammation. Previous studies showed that matrix metalloproteinase 12 knockout (

Indexed as

AnimalsAstrocytesCardiovirus InfectionsCell MovementGlial Fibrillary Acidic ProteinGliosisImmunophenotypingInflammationMacrophagesMatrix Metalloproteinase 12Mice, KnockoutMicrogliaPhenotypeSpinal CordGlial Fibrillary Acidic ProteinMatrix Metalloproteinase 12astrogliosischemokine receptor 2knockout miceM1M2matrix metalloproteinasesmicroglia phenotypeTheiler’s murine encephalomyelitis

Identifiers

PMID30959793
PMCPMC6480673
OpenAlexW2932968672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.