Evidence map›Paper›PMID 30959752›Full record

ReviewPharmaceuticals (Basel, Switzerland)2019

2018 FDA Tides Harvest.

Danah Al Shaer, Othman Al Musaimi, Fernando Albericio, Beatriz G de la Torre

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. RNA therapeutics: current status and future directions.Signal transduction and targeted therapy · 2026
    Review
  2. Eplontersen for the Treatment of Hereditary Transthyretin Amyloidosis.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Porous silicon and silica carriers for delivery of peptide therapeutics.Drug delivery and translational research · 2024
    Review
  5. Peptide-Based Therapeutics in Cancer Therapy.Molecular biotechnology · 2024
    Review
  6. Review
  7. 2023 FDA TIDES (Peptides and Oligonucleotides) Harvest.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  8. 2022 FDA TIDES (Peptides and Oligonucleotides) Harvest.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. Strategic Approaches to Improvise Peptide Drugs as Next Generation Therapeutics.International journal of peptide research and therapeutics · 2023
    Review
  10. Article
  11. Strategies for Improving Peptide Stability and Delivery.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Peptide Therapeutics 2.0.Molecules (Basel, Switzerland) · 2020
    Article
  18. Article
  19. 2019 FDA TIDES (Peptides and Oligonucleotides) Harvest.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danah Al ShaerKRISP, School of Laboratory of Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa. 217078895@stuukznac.onmicrosoft.com.
Othman Al MusaimiKRISP, School of Laboratory of Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa. 217078894@stuukznac.onmicrosoft.com.
Fernando AlbericioSchool of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa. albericio@ukzn.ac.za.ORCID 0000-0002-8946-0462
Beatriz G de la TorreKRISP, School of Laboratory of Medicine and Medical Science, College of Health Sciences, University of KwaZulu-Natal, Durban 4001, South Africa. garciadelatorreb@ukzn.ac.za.ORCID 0000-0001-8521-9172

Funding

Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya 2017 SGR 1439Ministerio de Economía y Competitividad CTQ2015-67870-PNational Research Foundation CSUR # 105892 and Blue Sky's Research Programme # 110960
6 · The paper itself

Abstract

In 2018, the United States Food and Drug Administration (FDA) approved a total of 59 new drugs, three of them (5%) are TIDES (or also, -tides), two oligonucleotides and one peptide. Herein, the three TIDES approved are analyzed in terms of medical target, mode of action, chemical structure, and economics.

Indexed as

dotatatedrugsinotersenLutatheraoligonucleotidesOnpattropatisiranpeptidespharmaceutical marketTegsedi

Identifiers

PMID30959752
PMCPMC6631726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.