Evidence map›Paper›PMID 30959582›Full record

ArticleIntestinal research2019

Clinical comparison of low-volume agents (oral sulfate solution and sodium picosulfate with magnesium citrate) for bowel preparation: the EASE study.

Jeeyeon Kim, Hyun Gun Kim, Kyeong Ok Kim, Hyung Wook Kim, Jongha Park, Jeong-Sik Byeon, Sung-Wook Hwang, Hyun Deok Shin, Jeong Eun Shin, Hyo-Joon Yang and 7 more

Abstract read
In one paragraph

Article in Intestinal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jeeyeon KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Hyun Gun KimDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Kyeong Ok KimDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Hyung Wook KimDepartment of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
Jongha ParkDepartment of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Jeong-Sik ByeonDepartment of Gastroenterology, University of Ulsan College of Medicine, Seoul, Korea.
Sung-Wook HwangDepartment of Gastroenterology, University of Ulsan College of Medicine, Seoul, Korea.
Hyun Deok ShinDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Jeong Eun ShinDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
Hyo-Joon YangDepartment of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hyun Seok LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Yunho JungDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Young-Seok ChoDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Young Eun JooDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Dae-Seong MyungDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Kyu Chan HuhDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea.
Eu Mi AhnDigestive Disease Center, Soonchunhyang University Hospital, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThis study compared the efficacy, compliance, and safety of bowel preparation between sodium picosulfate with magnesium citrate (SPMC) and oral sulfate solution (OSS).

methodsA prospective randomized multicenter study was performed. Split preparation methods were performed in both groups; the SPMC group, 2 sachets on the day before, and 1 sachet on the day of the procedure, the OSS group, half of the OSS with 1 L of water on both the day before and the day of the procedure. The adenoma detection rate (ADR), adequacy of bowel preparation using the Boston Bowel Preparation Scale (BBPS) score, patient satisfaction on a visual analog scale (VAS), and safety were compared between the 2 groups.

resultsThis study analyzed 229 patients (121 in the SPMC group and 108 in the OSS group). ADR showed no differences between 2 groups (51.7% vs. 41.7%, P> 0.05). The mean total BBPS score (7.95 vs. 8.11, P> 0.05) and adequate bowel preparation rate (94.9% vs. 96.3%, P> 0.05) were similar between the 2 groups. The mean VAS score for taste (7.62 vs. 6.87, P=0.006) was significantly higher in the SPMC group than in the OSS group. There were no significant differences in any other safety variables between the 2 groups except nausea symptom (36.1% vs. 20.3%, P=0.008).

conclusionsBowel preparation for colonoscopy using low volume OSS and SPMC yielded similar ADRs and levels of efficacy. SPMC had higher levels of satisfaction for taste and feeling than did OSS.

Indexed as

Bowel preparationColonoscopyOral sulfate solutionSodium picosulfate with magnesium citrate

Identifiers

PMID30959582
PMCPMC6667374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.