Evidence map›Paper›PMID 30959069›Full record

ReviewVirus research2019

African swine fever virus evasion of host defences.

L K Dixon, M Islam, R Nash, A L Reis

Open access · hybridAbstract readReview
In one paragraph

Review in Virus research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
27.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 186 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. The Involvement ofViruses · 2025
    Article
  18. Article
  19. Article
  20. Review

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L K DixonThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK. Electronic address: linda.dixon@pirbright.ac.uk.
M IslamThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK.
R NashThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK.
A L ReisThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey, GU24 0NF, UK.
The Pirbright Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/1/00007031, 7034Biotechnology and Biological Sciences Research Council BBS/E/I/00007034
6 · The paper itself

Abstract

African swine fever virus causes a haemorrhagic fever in domestic pigs and wild boar. The continuing spread in Africa, Europe and Asia threatens the global pig industry. The lack of a vaccine limits disease control. To underpin rational strategies for vaccine development improved knowledge is needed of how the virus interacts with and modulates the host's responses to infection. The virus long double-stranded DNA genome codes for more than 160 proteins of which many are non-essential for replication in cells but can have important roles in evading the host's defences. Here we review knowledge of the pathways targeted by ASFV and the mechanisms by which these are inhibited. The impact of deleting single or multiple ASFV genes on virus replication in cells and infection in pigs is summarised providing information on strategies for rational development of modified live vaccines.

Indexed as

Immune EvasionAfrican Swine FeverAfrican Swine Fever VirusAnimalsApoptosisInflammation MediatorsInterferon Type IMacrophagesSwineViral ProteinsViral VaccinesVirus ReplicationInflammation MediatorsInterferon Type IViral ProteinsViral VaccinesAfrican swine feverApoptosisCD2vImmune evasionInterferonPathogenesis

Identifiers

PMID30959069
PMCPMC6505686
OpenAlexW2929734527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.