ArticlePLoS biology2019
The amplitude in periodic neural state trajectories underlies the tempo of rhythmic tapping.
Article in PLoS biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- Abstract Representation of Movement Parameters in Basal Ganglia Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Manifolds in the Medial Premotor Cortex During Switching From Attending to Tapping to a Metronome.Annals of the New York Academy of Sciences · 2026Article
- Finding the groove in neural space.medRxiv : the preprint server for health sciences · 2026Article
- Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026Review
- Manifold properties in the macaque medial premotor cortex during switching from attending to tapping to a metronome.bioRxiv : the preprint server for biology · 2025Article
- Neural encoding of auditory rhythm beyond cortical auditory areas before the age of term.iScience · 2025Article
- A neuronal correlate for time interval estimation in the crow's telencephalon.Nature communications · 2025Article
- Revealing rhythm categorization in human brain activity.Science advances · 2025Article
- Priors and proprioceptive predictions.Current opinion in behavioral sciences · 2025Article
- Musical neurodynamics.Nature reviews. Neuroscience · 2025Review
- Article
- Contextual neural dynamics during time perception in the primate ventral premotor cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Measuring self-similarity in empirical signals to understand musical beat perception.The European journal of neuroscience · 2025Article
- Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity.Nature communications · 2024Article
- Rats synchronize predictively to metronomes.iScience · 2024Article
- Dynamical mechanisms of how an RNN keeps a beat, uncovered with a low-dimensional reduced model.Scientific reports · 2024Article
- Article
- Common neural mechanisms supporting time judgements in humans and monkeys.bioRxiv : the preprint server for biology · 2024Article
- Neuroimaging Signatures of Metacognitive Improvement in Sensorimotor Timing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Pre-supplementary Motor Cortex Mediates Learning Transfer from Perceptual to Motor Timing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our motor commands can be exquisitely timed according to the demands of the environment, and the ability to generate rhythms of different tempos is a hallmark of musical cognition. Yet, the neuronal underpinnings behind rhythmic tapping remain elusive. Here, we found that the activity of hundreds of primate medial premotor cortices (MPCs; pre-supplementary motor area [preSMA] and supplementary motor area [SMA]) neurons show a strong periodic pattern that becomes evident when their responses are projected into a state space using dimensionality reduction analysis. We show that different tapping tempos are encoded by circular trajectories that travelled at a constant speed but with different radii, and that this neuronal code is highly resilient to the number of participating neurons. Crucially, the changes in the amplitude of the oscillatory dynamics in neuronal state space are a signature of duration encoding during rhythmic timing, regardless of whether it is guided by an external metronome or is internally controlled and is not the result of repetitive motor commands. This dynamic state signal predicted the duration of the rhythmically produced intervals on a trial-by-trial basis. Furthermore, the increase in variability of the neural trajectories accounted for the scalar property, a hallmark feature of temporal processing across tasks and species. Finally, we found that the interval-dependent increments in the radius of periodic neural trajectories are the result of a larger number of neurons engaged in the production of longer intervals. Our results support the notion that rhythmic timing during tapping behaviors is encoded in the radial curvature of periodic MPC neural population trajectories.
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