Evidence map›Paper›PMID 30958812›Full record

ArticlePLoS computational biology2019

BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis.

Remco Bouckaert, Timothy G Vaughan, Joëlle Barido-Sottani, Sebastián Duchêne, Mathieu Fourment, Alexandra Gavryushkina, Joseph Heled, Graham Jones, Denise Kühnert, Nicola De Maio and 15 more

Abstract readValidation Study
In one paragraph

Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,812 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,812citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,812 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Physiology mediates transcontinental radiations of freshwater fishes.bioRxiv : the preprint server for biology · 2026
    Article

1,752 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Remco BouckaertCentre of Computational Evolution, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-6765-3813
Timothy G VaughanETH Zürich, Department of Biosystems Science and Engineering, 4058 Basel, Switzerland.
Joëlle Barido-SottaniETH Zürich, Department of Biosystems Science and Engineering, 4058 Basel, Switzerland.ORCID 0000-0002-5220-5468
Sebastián DuchêneDepartment of Biochemistry and Molecular Biology, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-2863-0907
Mathieu Fourmentithree institute, University of Technology Sydney, Sydney, Australia.ORCID 0000-0001-8153-9822
Alexandra GavryushkinaDepartment of Biochemistry, University of Otago, Dunedin 9016, New Zealand.
Joseph HeledIndependent researcher, Auckland, New Zealand.ORCID 0000-0002-2403-7997
Graham JonesDepartment of Biological and Environmental Sciences, University of Gothenburg, Box 461, SE 405 30 Göteborg, Sweden.ORCID 0000-0002-9686-5871
Denise KühnertMax Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0002-5657-018X
Nicola De MaioEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, UK.ORCID 0000-0002-1776-8564
Michael MatschinerDepartment of Environmental Sciences, University of Basel, 4051 Basel, Switzerland.
Fábio K MendesCentre of Computational Evolution, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-6204-7208
Nicola F MüllerETH Zürich, Department of Biosystems Science and Engineering, 4058 Basel, Switzerland.
Huw A OgilvieDepartment of Computer Science, Rice University, Houston, TX 77005-1892, USA.ORCID 0000-0003-1589-6885
Louis du PlessisDepartment of Zoology, University of Oxford, Oxford, OX1 3PS, UK.
Alex PopingaCentre of Computational Evolution, University of Auckland, Auckland, New Zealand.
Andrew RambautInstitute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, EH9 3FL UK.
David RasmussenDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695, USA.
Igor SiveroniDepartment of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, W2 1PG, UK.ORCID 0000-0003-2595-3062
Marc A SuchardDepartment of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID 0000-0001-9818-479X
Chieh-Hsi WuDepartment of Statistics, University of Oxford, OX1 3LB, UK.
Dong XieCentre of Computational Evolution, University of Auckland, Auckland, New Zealand.
Chi ZhangInstitute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0001-6009-5273
Tanja StadlerETH Zürich, Department of Biosystems Science and Engineering, 4058 Basel, Switzerland.ORCID 0000-0001-6431-535X
Alexei J DrummondCentre of Computational Evolution, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-4454-2576

Funding

Modeling Epidemic Infectious Diseases Using Sequence AnalysisU01GM110749 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POND, SERGEI L KOSAKOVSKY · 2014 to 2018
$3.0M
NIGMS NIH HHS U01 GM110749
6 · The paper itself

Abstract

Elaboration of Bayesian phylogenetic inference methods has continued at pace in recent years with major new advances in nearly all aspects of the joint modelling of evolutionary data. It is increasingly appreciated that some evolutionary questions can only be adequately answered by combining evidence from multiple independent sources of data, including genome sequences, sampling dates, phenotypic data, radiocarbon dates, fossil occurrences, and biogeographic range information among others. Including all relevant data into a single joint model is very challenging both conceptually and computationally. Advanced computational software packages that allow robust development of compatible (sub-)models which can be composed into a full model hierarchy have played a key role in these developments. Developing such software frameworks is increasingly a major scientific activity in its own right, and comes with specific challenges, from practical software design, development and engineering challenges to statistical and conceptual modelling challenges. BEAST 2 is one such computational software platform, and was first announced over 4 years ago. Here we describe a series of major new developments in the BEAST 2 core platform and model hierarchy that have occurred since the first release of the software, culminating in the recent 2.5 release.

Indexed as

Bayes TheoremBiological EvolutionPhylogenySoftwareAnimalsComputational BiologyComputer SimulationEvolution, MolecularHumansMarkov ChainsModels, GeneticMonte Carlo Method

Identifiers

PMID30958812
PMCPMC6472827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.