ArticleChinese medical journal2019
Development and validation of a preoperative nomogram for predicting positive surgical margins after laparoscopic radical prostatectomy.
Article in Chinese medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinicopathological Significances of Positive Surgical Resection Margin after Radical Prostatectomy for Prostatic Cancers: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Predictive Factors for Positive Surgical Margins in Patients With Prostate Cancer After Radical Prostatectomy: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2020Pooled it
- An interpretable nomogram for positive surgical margin risk after laparoscopic and robot-assisted radical prostatectomy: a single-centre development and internal validation study.Journal of robotic surgery · 2026Article
- Relationship between the status of positive surgical margins and biochemical recurrence: developing a risk stratification model for biochemical recurrence following radical prostatectomy.Journal of robotic surgery · 2026Article
- Preoperative dual-ROI mpMRI radiomics integrating intratumoral and periprostatic adipose tissue features with clinical factors for predicting positive surgical margins after radical prostatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
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- Lesion-based grading system using clinicopathological and MRI features for predicting positive surgical margins in prostate cancer.Abdominal radiology (New York) · 2025Article
- Development of preoperative nomograms to predict the risk of overall and multifocal positive surgical margin after radical prostatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- The value of preoperative neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and red blood cell distribution width in predicting positive surgical margin after laparoscopic radical prostatectomy.Cancer reports (Hoboken, N.J.) · 2024Article
- An MRI-based grading system for preoperative risk estimation of positive surgical margin after radical prostatectomy.Insights into imaging · 2023Article
- Analysis of risk factors for positive surgical margin after laparoscopic radical prostatectomy with and without neoadjuvant hormonal therapy.Frontiers in endocrinology · 2023Article
- Value of three-dimensional visualization of preoperative prostatic magnetic resonance imaging based on measurements of anatomical structures in predicting positive surgical margin after radical prostatectomy.Frontiers in endocrinology · 2023Article
- Development of a Prediction Model for Positive Surgical Margin in Robot-Assisted Laparoscopic Radical Prostatectomy.Current oncology (Toronto, Ont.) · 2022Article
- Multiparametric MRI-based nomograms in predicting positive surgical margins of prostate cancer after laparoscopic radical prostatectomy.Frontiers in oncology · 2022Article
- Prediction of a positive surgical margin and biochemical recurrence after robot-assisted radical prostatectomy.Scientific reports · 2021Article
- Preoperative MRI-based estimation of risk for positive resection margin after radical prostatectomy in patients with prostate cancer: development and validation of a simple scoring system.European radiology · 2021Article
- Preoperative prostate magnetic resonance imaging does not impact surgical outcomes of radical prostatectomy.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
- Evaluating Incidence, Location, and Predictors of Positive Surgical Margin Among Chinese Men Undergoing Robot-Assisted Radical Prostatectomy.Cancer control : journal of the Moffitt Cancer CenterArticle
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11 authors.
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Abstract
backgroundPositive surgical margins are independent risk factor for biochemical recurrence, local recurrence, and distant metastasis after radical prostatectomy. However, limited predictive tools are available. This study aimed to develop and validate a preoperative nomogram for predicting positive surgical margins after laparoscopic radical prostatectomy (LRP).
methodsFrom January 2010 to March 2016, a total of 418 patients who underwent LRP without receiving neoadjuvant therapy at Peking University Third Hospital were retrospectively involved in this study. Clinical and pathological results of each patient were collected for further analysis. Univariable and multivariable logistic regression (backward stepwise method) were used for the nomogram development. The concordance index (CI), calibration curve analysis and decision curve analysis were used to evaluate the performance of our model.
resultsOf 418 patients involved in this study, 142 patients (34.0%) had a positive surgical margin on final pathology. Based on the backward selection, four variables were included in the final multivariable regression model, including the percentage of positive cores in preoperative biopsy, clinical stage, free prostate specific antigen (fPSA)/total PSA (tPSA), and age. A nomogram was developed using these four variables. The concordance index (C-index) of the nomogram was 0.722 in the development cohort and 0.700 in the bootstrap validations. The bias-corrected calibration plot showed a limited departure from the ideal line with a mean absolute error of 2.0%. In decision curve analyses, the nomogram showed net benefits in the range from 0.2 to 0.7.
conclusionA nomogram to predict positive surgical margins after LRP was developed and validated, which could help urologists plan surgical procedures.
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