ArticleJournal of Alzheimer's disease : JAD2019
Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants.
Article in Journal of Alzheimer's disease : JAD, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Association Between the Genetic Risk for Attention-Deficit/Hyperactivity Disorder and Cognitive Function in Older Age: The MYHAT Population-Based Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Pathways to participation - a scoping review outlining barriers and enablers to participation in dementia research.The journal of prevention of Alzheimer's disease · 2026Article
- The Alzheimer's Disease Neuroimaging Initiative-4 (ADNI-4) Engagement Core: A culturally informed, community-engaged research (CI-CER) model to advance brain health equity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Digital culturally tailored marketing for enrolling Latino participants in a web-based registry: Baseline metrics from the Brain Health Registry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- The Community Engaged Digital Alzheimer's Research (CEDAR) Study: A Digital Intervention to Increase Research Participation of Black American Participants in the Brain Health Registry.The journal of prevention of Alzheimer's disease · 2023Article
- Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI).Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Remote blood collection from older adults in the Brain Health Registry for plasma biomarker and genetic analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Development and implementation of an electronic Clinical Dementia Rating and Financial Capacity Instrument-Short Form.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Brain health registry GenePool study: A novel approach to online genetics research.Alzheimer's & dementia (New York, N. Y.) · 2021Article
- Effects of sex, race, ethnicity, and education on online aging research participation.Alzheimer's & dementia (New York, N. Y.) · 2020Article
- Digital efforts in Spanish for enrolling Latino adults in the Brain Health Registry.Alzheimer's & dementia (New York, N. Y.)Article
- Community-engaged efforts to increase retention of Black American online registry participants.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundGenetic data help detect preclinical Alzheimer's disease and target individuals for clinical trials, making genetic research engagement critical for continued advancement in dementia prevention and treatment.
objectiveTo understand what individual and institutional factors may relate to provision of genetic samples within the Alzheimer's Disease Centers.
methodsData from the National Alzheimer's Coordinating Center Uniform Data Set (2009-2016) were obtained along with genetic sample availability. Logistic regression was used to assess independent contributions of demographic and clinical characteristics to the probability of sample provision. Sites contributing data completed a brief survey exploring regulatory and scientific issues related to genetic research engagement.
resultsJust over half (52.1%) of the 27,519 unique participants had genetic data available. Female sex, white race, non-Hispanic ethnicity, normal cognition, and greater than 5 years of follow-up were associated with greater probability of availability. Sites identified refusals as the most frequent barrier to sample provision, followed by staff availability.
conclusionThese results highlight the importance of strategies to promote minority engagement and encourage earlier genetic research participation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.