Evidence map›Paper›PMID 30958158›Full record

ArticleJournal of the Royal Society, Interface2019

Eggshell spheres protect brown widow spider ( Latrodectus geometricus) eggs from bacterial infection.

Vardit Makover, Zeev Ronen, Yael Lubin, Isam Khalaila

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Modulating Surface Properties of theBiomacromolecules · 2021
    Article
  8. Article
  9. Widow spiders in the New World: a review onThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vardit Makover1 Department of Environmental Hydrology and Microbiology, Zuckerberg Institute for Water Research, Blaustein Institutes for Desert Research, Ben-Gurion University , Midreshet Ben-Gurion , Israel.
Zeev Ronen1 Department of Environmental Hydrology and Microbiology, Zuckerberg Institute for Water Research, Blaustein Institutes for Desert Research, Ben-Gurion University , Midreshet Ben-Gurion , Israel.
Yael Lubin2 Marco and Louise Mitrani Department of Desert Ecology, Blaustein Institutes for Desert Research, Ben-Gurion University , Midreshet Ben-Gurion , Israel.
Isam Khalaila3 Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University , Beer Sheva , Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eggs provide a rich source of nutrients for the developing embryo, making them a favoured food source for other organisms as well. Several defence mechanisms have evolved to protect the developing embryos against microbial threats. In this article, we elucidate the defence strategy of brown widow spider ( Latrodectus geometricus) eggs against bacteria. Antibacterial activity was shown by inhibition of bacterial growth on agar plate, liquid culture and retarded biofilm formation. The defence strategy against bacterial invasion was demonstrated in the whole egg, whole egg extract, egg surface extract, eggshell and eggshell extract. The source and characteristics of this antibacterial activity are distinctive and stem in part from a dense layer of spheres covering the egg surface, likely originated from the oviposition fluid. The spheres are rich in low-molecular-weight proteins, yet their exact composition remains unknown. In this study, we demonstrate that the egg surface is hydrophobic, while the spheres are superhydrophilic. Egg surface roughness and hydrophobicity combined with its antibacterial chemical properties reduce the ability of bacteria to grow on the egg surface. Understanding the properties of these unique structures may contribute significantly to our knowledge of how nature deals with bacterial infections.

Indexed as

Anti-Bacterial AgentsArthropod ProteinsAnimalsBacteriaBacterial InfectionsEgg ShellFemaleSpidersAnti-Bacterial AgentsArthropod Proteinsantibacterialegg surfacespheresspider

Identifiers

PMID30958158
PMCPMC6364662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.