Evidence map›Paper›PMID 30958098›Full record

ReviewOpen biology2019

Faster, higher, stronger: timely and robust cell fate/identity commitment in stem cell lineages.

Kun Liu, Ke Xu, Yan Song

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Open biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Yan Song: How time flies.The Journal of cell biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kun Liu1 Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences , Beijing 100871 , People's Republic of China.
Ke Xu1 Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences , Beijing 100871 , People's Republic of China.
Yan Song1 Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences , Beijing 100871 , People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise specification of cell fate or identity within stem cell lineages is critical for ensuring correct stem cell lineage progression and tissue homeostasis. Failure to specify cell fate or identity in a timely and robust manner can result in developmental abnormalities and diseases such as cancer. However, the molecular basis of timely cell fate/identity specification is only beginning to be understood. In this review, we discuss key regulatory strategies employed in cell fate specification and highlight recent results revealing how timely and robust cell fate/identity commitment is achieved through transcriptional control.

Indexed as

Models, BiologicalAnimalsAsymmetric Cell DivisionCell DifferentiationCell LineageCell ProliferationDrosophila melanogasterGene Expression RegulationReceptors, NotchStem CellsReceptors, Notchamplifiercell fate commitmentDrosophila melanogasterpoisingstem cell lineagestimeliness

Identifiers

PMID30958098
PMCPMC6395883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.