Evidence map›Paper›PMID 30957634›Full record

ArticleAutophagy2020

The

Julia A Thayer, Ola Awad, Nivedita Hegdekar, Chinmoy Sarkar, Henok Tesfay, Cameran Burt, Xianmin Zeng, Ricardo A Feldman, Marta M Lipinski

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  16. 1-L Transcription of SARS-CoV-2 Spike Protein S1 Subunit.International journal of molecular sciences · 2024
    Article
  17. Review
  18. Article
  19. Ubiquitination in the regulation of autophagy.Acta biochimica et biophysica Sinica · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Julia A ThayerDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Ola AwadDepartment of Microbiology and Immunology.
Nivedita HegdekarDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Chinmoy SarkarDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Henok TesfayDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Cameran BurtDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
Xianmin ZengXCell Science Inc, Novato, CA, USA.
Ricardo A FeldmanDepartment of Microbiology and Immunology.
Marta M LipinskiDepartment of Anesthesiology & Shock, Trauma and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · USXCell Science (United States) · US

Funding

The new roles of the autophagy-lysosomal pathway in spinal cord injury-mediated dementiaR01NS094527 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI MARTA M LIPINSKI, Junfang Wu · 2016 to 2026
$3.5M
Function and Mechanisms of Autophagy-Lysosomal Pathway in Traumatic Brain InjuryR01NS091218 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI LIPINSKI, MARTA M · 2015 to 2019
$1.8M
The PARK10 gene USP24 affects Parkinson's Disease via regulation of autophagyR03NS087338 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI LIPINSKI, MARTA M · 2014 to 2015
$154k
NINDS NIH HHS R01 NS091218NINDS NIH HHS R01 NS094527NINDS NIH HHS R03 NS087338
6 · The paper itself

Abstract

Recent studies indicate a causative relationship between defects in autophagy and dopaminergic neuron degeneration in Parkinson disease (PD). However, it is not fully understood how autophagy is regulated in the context of PD. Here we identify

Indexed as

AutophagyAutophagy-Related Protein-1 HomologHumansIntracellular Signaling Peptides and ProteinsParkinson DiseaseTranscription FactorsUbiquitin ThiolesteraseAutophagy-Related Protein-1 HomologIntracellular Signaling Peptides and ProteinsTranscription FactorsUbiquitin ThiolesteraseULK1 protein, humanUSP24 protein, humanAutophagydopaminergic neuronsinduced-pluripotent stem cellsParkinson diseaseUSP24

Identifiers

PMID30957634
PMCPMC6984603
OpenAlexW2939853343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.