Evidence map›Paper›PMID 30957407›Full record

ArticleThoracic cancer2019

Nomogram to predict thymoma prognosis: A population-based study of 1312 cases.

Mengnan Zhao, Jiacheng Yin, Xiaodong Yang, Tian Jiang, Tao Lu, Yiwei Huang, Ming Li, Xinyu Yang, Miao Lin, Hao Niu and 3 more

Abstract read
In one paragraph

Article in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  17. [Myasthenia gravis].Der Nervenarzt · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mengnan ZhaoDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiacheng YinDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiaodong YangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Tian JiangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Tao LuDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Yiwei HuangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Ming LiDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xinyu YangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Miao LinDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao NiuDepartment of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Cheng ZhanDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-8745-9276
Mingxiang FengDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-0372-8860
Qun WangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA thymoma is a common cancer within the anterior mediastinum; however, the prognostic characteristics have not been established. The aim of this study was to identify the prognostic factors and develop a nomogram for the prognostic prediction of patients with thymoma based on data from the Surveillance, Epidemiology, and End Results (SEER) database.

methodsPatients with thymomas diagnosed between 1983 and 2014 were selected. Overall survival (OS) was estimated using the Kaplan-Meier method with the log-rank test. Univariate and multivariate Cox proportional hazards regression analyses were performed to identify the independent prognostic factors, from which a nomogram for thymomas was created. External validation of the nomogram was performed using data from our center.

resultsA total of 1312 patients with thymomas were enrolled. Age, tumor size, Masaoka-Koga stage, chemotherapy administered, and surgery type were independent prognostic factors for OS. A nomogram for OS was formulated based on the independent prognostic factors and validated using an internal bootstrap resampling approach, which showed that the nomogram exhibited a sufficient level of discrimination according to the C-index in training (0.713, 95% confidence interval 0.685-0.741) and (0.746, 95% confidence interval 0.625-0.867) validation cohorts.

conclusionSeveral prognostic factors for thymomas were identified. The nomogram developed in this study accurately predicted the 5-year and 10-year OS rates of patients with thymomas based on individual characteristics. Risk stratification using the survival nomogram could optimize individual therapy and follow-up.

Indexed as

AdultAgedAged, 80 and overFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNomogramsPopulation SurveillancePrognosisSEER ProgramThymomaNomogramprognostic factorSEER databasethymoma

Identifiers

PMID30957407
PMCPMC6500983

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.